Survival analysis of patients with primary gallbladder cancer from 2010 to 2015 A retrospective study based on SEER data
文献类型：期刊论文
| 作者 | Zhu, Xiaolei1; Zhang, Xiaochang1; Hu, Xiao2; Ren, Hongyan3 ; Wu, Shenghui4; Wu, Jing5; Wu, Guoyi6; Si, Xiang1; Wang, Baohua5
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| 刊名 | MEDICINE
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| 出版日期 | 2020-10-02 |
| 卷号 | 99期号:40页码:6 |
| 关键词 | primary gallbladder cancer prognosis survival |
| ISSN号 | 0025-7974 |
| DOI | 10.1097/MD.0000000000022292 |
| 通讯作者 | Wu, Jing(wujingcdc42@163.com) ; Wu, Guoyi() |
| 英文摘要 | This study aims to assess the survival status of patients with Primary gallbladder cancer (PGC) and analyze the prognosis factors to facilitate the exploration of the prevention and therapeutic strategies of PGC. Data from 2433 PGC patients collected from 2010 to 2015 were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. The SEER*Stat, SPSS 23.0 and GraphPad Prism 8 were used for statistical analyses. Kaplan Meier analysis was performed for the survival curve, log-rank test analyses were used to compare the survival rate difference and Cox regression analyses were performed to determine the prognosis factors. A total of 2433 PGC cases were reported from 2010 to 2015. The median age was 64.2 +/- 10.4 years old and the percentages of the white patients were 73.7% (1794/2433). The percentage of patients who received surgery treatment was 82.1% (1998/2433). The overall median survival time of all patients was 19 months and the 5-year survival rate was 28.8%. The 5-year survival rate of PGC patients in pN2 stage dropped to 0% and the 5-year survival rate for PGC patients with distant metastasis was only 2.7%. Age, tumor size, grade, pT stage, pM stage were risk factors for prognosis, surgery or not and radiation or not were protective factors for prognosis. Survival analysis of PGC patients based on the SEER database have provided an opportunity for understanding PGC prognosis and the basis for the exploration of viable PGC prevention and therapeutic strategies. |
| WOS关键词 | RISK |
| 资助项目 | National Key Research and Development Program of Ministry of Science and Technology of China[2016YFC1302600] ; Integrated Cancer Prevention and Control in the Huai River Program |
| WOS研究方向 | General & Internal Medicine |
| 语种 | 英语 |
| WOS记录号 | WOS:000579119300026 |
| 出版者 | LIPPINCOTT WILLIAMS & WILKINS |
| 资助机构 | National Key Research and Development Program of Ministry of Science and Technology of China ; Integrated Cancer Prevention and Control in the Huai River Program |
| 源URL | [http://ir.igsnrr.ac.cn/handle/311030/157117]  |
| 专题 | 中国科学院地理科学与资源研究所 |
| 通讯作者 | Wu, Jing; Wu, Guoyi |
| 作者单位 | 1.Chinese Ctr Dis Control & Prevent, Off Noncommunicable Dis Control & Aging Hlth, Beijing, Peoples R China 2.Beijing Ctr Dis Control & Prevent, Informat Ctr, Beijing, Peoples R China 3.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Beijing, Peoples R China 4.Univ Texas Hlth San Antonio, Dept Epidemiol & Biostat, San Antonio, TX USA 5.Chinese Ctr Dis Control & Prevent, Natl Ctr Chron & Noncommunicable Dis Control & Pr, 27 Nanwei Rd, Beijing, Peoples R China 6.Fudan Univ, Shanghai Publ Hlth Clin Ctr, 2901 Caolang Rd, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Xiaolei,Zhang, Xiaochang,Hu, Xiao,et al. Survival analysis of patients with primary gallbladder cancer from 2010 to 2015 A retrospective study based on SEER data[J]. MEDICINE,2020,99(40):6. |
| APA | Zhu, Xiaolei.,Zhang, Xiaochang.,Hu, Xiao.,Ren, Hongyan.,Wu, Shenghui.,...&Wang, Baohua.(2020).Survival analysis of patients with primary gallbladder cancer from 2010 to 2015 A retrospective study based on SEER data.MEDICINE,99(40),6. |
| MLA | Zhu, Xiaolei,et al."Survival analysis of patients with primary gallbladder cancer from 2010 to 2015 A retrospective study based on SEER data".MEDICINE 99.40(2020):6. |
入库方式： OAI收割
来源：地理科学与资源研究所
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