RISK ASSESSMENT OF ANTIBIOTIC PREVALENCE IN DRINKING WATER AND ITS IMPACTS ON HUMAN HEALTH IN CHINA
文献类型：期刊论文
| 作者 | Lyu, J.1,2,3; Yang, L. S.2,3; Chen, Y. Y.1; Ye, B. X.1; Zhang, L.1; Wang, L.2 |
| 刊名 | APPLIED ECOLOGY AND ENVIRONMENTAL RESEARCH
 |
| 出版日期 | 2021 |
| 卷号 | 19期号:1页码:219-236 |
| ISSN号 | 1589-1623 |
| 关键词 | pollution exposure macrolides sulfonamides fluoroquinolones |
| DOI | 10.15666/aeer/1901_219236 |
| 通讯作者 | Zhang, L.(zhanglan@nieh.chinacdc.cn) ; Wang, L.(wangli@igsnrr.ac.cn) |
| 英文摘要 | Drinking water is a known potential source of human exposure to antibiotics. However, risk of antibiotic exposure from drinking water has not been sufficiently quantified. We measured the levels of 23 antibiotics in drinking water from 12 cities of China during the summer and winter seasons, quantifying exposure doses and health risk quotients (HRQ) of antibiotic exposure via drinking water. High detection rates (above 70%) of macrolides (MLs), sulfonamides and fluoroquinolones were observed during summer season, with median concentrations of 0.26 ng/L, 0.59 ng/L and 0.36 ng/L, respectively, while only MLs were observed with a high detection rate in winter (median concentration 0.46 ng/L). Total antibiotic exposure via drinking water ranged from 0.0036 ng/kg/day to 4.36 ng/kg/day in summer and from 0.0046 ng/kg/day to 1.12 ng/kg/day in winter. High median antibiotic exposures were observed in Chaohu, Huainan and Guangzhou in summer and in Mudanjiang in winter. Of the 18 detected antibiotics, enrofloxacin, ciprofloxacin, sarafloxacin and roxithromycin had an HRQ >= 0.01. Drinking water is one of the principal pathways for human exposure to antibiotics. Accordingly, management of antibiotic exposure from drinking water should be a high public health priority, and the accompanying health risks merit greater attention from public health authorities. |
| 资助项目 | National Key R&D Program of China[2018YFC0407502] ; National Key R&D Program of China[2016YFD0801004] ; Science and Technology Project of Beautiful China Ecological Civilization Construction[XDA23100403] ; Young Elite Scientist Sponsorship Program of Beijing Association for Science and Technology[20202022] |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| 出版者 | CORVINUS UNIV BUDAPEST |
| WOS记录号 | WOS:000637972200016 |
| 资助机构 | National Key R&D Program of China ; Science and Technology Project of Beautiful China Ecological Civilization Construction ; Young Elite Scientist Sponsorship Program of Beijing Association for Science and Technology |
| 源URL | [http://ir.igsnrr.ac.cn/handle/311030/161752]  |
| 专题 | 中国科学院地理科学与资源研究所 |
| 通讯作者 | Zhang, L.; Wang, L. |
| 作者单位 | 1.Chinese Ctr Dis Control & Prevent, Natl Inst Environm Hlth, China CDC Key Lab Environm & Populat Hlth, 29 Nanwei Rd, Beijing 100050, Peoples R China 2.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Key Lab Land Surface Pattern & Simulat, 11A Datun Rd, Beijing 100101, Peoples R China 3.Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lyu, J.,Yang, L. S.,Chen, Y. Y.,et al. RISK ASSESSMENT OF ANTIBIOTIC PREVALENCE IN DRINKING WATER AND ITS IMPACTS ON HUMAN HEALTH IN CHINA[J]. APPLIED ECOLOGY AND ENVIRONMENTAL RESEARCH,2021,19(1):219-236. |
| APA | Lyu, J.,Yang, L. S.,Chen, Y. Y.,Ye, B. X.,Zhang, L.,&Wang, L..(2021).RISK ASSESSMENT OF ANTIBIOTIC PREVALENCE IN DRINKING WATER AND ITS IMPACTS ON HUMAN HEALTH IN CHINA.APPLIED ECOLOGY AND ENVIRONMENTAL RESEARCH,19(1),219-236. |
| MLA | Lyu, J.,et al."RISK ASSESSMENT OF ANTIBIOTIC PREVALENCE IN DRINKING WATER AND ITS IMPACTS ON HUMAN HEALTH IN CHINA".APPLIED ECOLOGY AND ENVIRONMENTAL RESEARCH 19.1(2021):219-236. |
入库方式： OAI收割
来源：地理科学与资源研究所
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