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Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin

文献类型：期刊论文

作者Wang, Jiangru3; Chen, Xiaolan3; Wang, Xiaoyan2; Kang, Qi3; Shen, Dazhong3; Chen, Lingxin1
刊名SENSORS AND ACTUATORS B-CHEMICAL
出版日期2020-11-01
卷号322页码:9
关键词Molecular imprinting Ratiometric fluorescence Differential measurement Smartphone Bovine hemoglobin
DOI10.1016/j.snb.2020.128581
通讯作者Shen, Dazhong(dzshen@sdnu.edu.cn) ; Chen, Lingxin()
英文摘要The non-specific adsorption of interferents onto the outside surface of molecularly imprinted polymers (MIPs) particles is disadvantageous for selective determination of the template molecules. Based on the fact that the responses of non-imprinted polymers (NIPs) and MIPs particles to non-template molecules are similar, the anti-interference ability of MIPs sensor can be much improved via differential strategy, demonstrated by bovine hemoglobin (BHb) determination. The MIPs for BHb were prepared via surface imprinting and sol-gel process, with graphene quantum dots@SiO2/CdTe quantum dots (GODs@SiO2/CdTe QDs) for ratiometric fluorescence measurements. By using a weight factor of 1.283 to compensate the lower specific surface area in NIPs particles, the differential ratiometric fluorescence signals between MIPs and NIPs channels to 2.00 mu M ovalbumin and phycocyanin are equivalent to BHb at the concentration of 0.025 and 0.014 mu M, which are only about 11 % and 5.8 % of the interference level in the normal ratiometric fluorescence method, respectively. The differential ratiometric fluorescence measurement was also performed in a smartphone-based device for field analysis of BHb in urine samples, with the linear range of 0.05-4 mu M and the detection limit of 13 nM.
WOS关键词SELECTIVE RECOGNITION ; SENSITIVE DETECTION ; QUANTUM DOTS ; SMARTPHONE ; POLYMERS ; NANOPARTICLES ; PERFORMANCE
资助项目National Natural Science Foundation of China[21874083] ; National Natural Science Foundation of China[21976209] ; National Natural Science Foundation of China[21804010] ; Natural Science Foundation of Shandong Province of China[ZR2018MB029] ; Taishan Scholar Project Special Fund[ts20190962]
WOS研究方向Chemistry ; Electrochemistry ; Instruments & Instrumentation
语种英语
WOS记录号WOS:000573296800001
资助机构National Natural Science Foundation of China ; Natural Science Foundation of Shandong Province of China ; Taishan Scholar Project Special Fund
源URL[http://ir.yic.ac.cn/handle/133337/28496]  
专题烟台海岸带研究所_山东省海岸带环境工程技术研究中心
烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
通讯作者Shen, Dazhong; Chen, Lingxin
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
2.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
3.Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Mol & Nano Probes, Minist Educ, Jinan 250014, Peoples R China
推荐引用方式
GB/T 7714		 Wang, Jiangru,Chen, Xiaolan,Wang, Xiaoyan,et al. Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin[J]. SENSORS AND ACTUATORS B-CHEMICAL,2020,322:9.
APA Wang, Jiangru,Chen, Xiaolan,Wang, Xiaoyan,Kang, Qi,Shen, Dazhong,&Chen, Lingxin.(2020).Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin.SENSORS AND ACTUATORS B-CHEMICAL,322,9.
MLA Wang, Jiangru,et al."Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin".SENSORS AND ACTUATORS B-CHEMICAL 322(2020):9.

入库方式： OAI收割

来源：烟台海岸带研究所

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