Prevalence and Prescription of Antidepressants in Depression with Somatic Comorbidity in Asia: The Research on East Asian Psychotropic Prescription Patterns Study
文献类型：期刊论文
| 作者 | Chen Chao8; Si TianMei8; Xiang YuTao10; Ungvari Gabor S6; Wang ChuanYue5; He YanLing4; Kua EeHeok3; Fujii Senta2; Sim Kang1; Trivedi Jitendra K17 |
| 刊名 | Chinese Medical Journal
 |
| 出版日期 | 2015 |
| 卷号 | 128期号:7页码:853-858 |
| 关键词 | Asia Medicine R Depression Prescription Prevalence Somatic Comorbidity |
| ISSN号 | 0366-6999 |
| 其他题名 | Prevalence and Prescription of Antidepressants in Depression with Somatic Comorbidity in Asia: The Research on East Asian Psychotropic Prescription Patterns Study |
| 英文摘要 | Background: Depression is often comorbid with chronic somatic diseases. Few previous studies have investigated the prevalence of somatic diseases in depression or the prescription pattern of antidepressants in comorbidly depressed patients in Asia. This study aimed to investigate the prevalence of somatic comorbidity (SC) in depression and compared the prescriptions of antidepressants in depressed patients with and without SC. Methods: A total of 2320 patients treated with antidepressants in 8 Asian countries were examined, and a diagnosis was based on the International Classification of Disease, 10 th revision. We listed 17 common chronic somatic diseases. Patients′ socio-demographic and clinical characteristics and psychotropic drug prescriptions were recorded using a standardized protocol and data collection procedure. Results: Of the patients examined, 1240 were diagnosed with depression and 30% of them (n = 375) had SC. The most common comorbid condition was diabetes (23.7%). The patients with SC were more likely to seek help at a general hospital (74.7% vs. 47.2%), and had a higher incidence of symptoms involving sadness, disturbed sleep, and poor appetite. Noradrenergic and specific serotonergic antidepressant was prescribed more for patients with SC than for those without SC (30.4% vs. 22.9%). Conclusions: SC is common in depressed Asian patients. It is important to strengthen the recognition of depression, especially in general hospitals and when patients report some somatic discomfort. It is also a matter of urgency to establish evidence-based guidelines for the use of new antidepressants in depressed patients with SC. |
| 资助项目 | ["12th Five-year-plan" of National Key Technologies R and D Program of China] ; [Research Fund for the Doctoral Program of Higher Education of China] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:5392544 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/36515]  |
| 专题 | 心理研究所_健康与遗传心理学研究室 |
| 作者单位 | 1.Institute Mental Hlth, Singapore, Singapore 2.Fukushima Med University, Dept Disaster Psychiat, Fukushima, Japan 3.Natl University Singapore, Dept Psychol Med, Singapore 117548, Singapore 4.Shanghai Mental Hlth Ctr, Shanghai 200030, Peoples R China 5.Capital Med University, Beijing Anding Hosp, Beijing 100088, Peoples R China 6.University Western Australia, Sch Psychiat & Clin Neurosci, Perth, WA 6009, Australia 7.Chinese University Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China Dept Psychiat 8.中国科学院心理研究所 9.北京大学 10.University Macau, Fac Hlth Sci, Macau, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen Chao,Si TianMei,Xiang YuTao,et al. Prevalence and Prescription of Antidepressants in Depression with Somatic Comorbidity in Asia: The Research on East Asian Psychotropic Prescription Patterns Study[J]. Chinese Medical Journal,2015,128(7):853-858. |
| APA | Chen Chao.,Si TianMei.,Xiang YuTao.,Ungvari Gabor S.,Wang ChuanYue.,...&Shinfuku Naotaka.(2015).Prevalence and Prescription of Antidepressants in Depression with Somatic Comorbidity in Asia: The Research on East Asian Psychotropic Prescription Patterns Study.Chinese Medical Journal,128(7),853-858. |
| MLA | Chen Chao,et al."Prevalence and Prescription of Antidepressants in Depression with Somatic Comorbidity in Asia: The Research on East Asian Psychotropic Prescription Patterns Study".Chinese Medical Journal 128.7(2015):853-858. |
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来源：心理研究所
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