The effect of effort-reward imbalance on brain structure and resting-state functional connectivity in individuals with high levels of schizotypal traits
文献类型:期刊论文
作者 | Yan, Yong-jie5,6,7; Huang, Jia4,7; Lui, Simon S. Y.2,8; Cheung, Eric F. C.2; Madsen, Kristoffer H.1,3,5,6; Chan, Raymond C. K.4,5,6,7 |
刊名 | COGNITIVE NEUROPSYCHIATRY |
出版日期 | 2021-03-12 |
页码 | 17 |
ISSN号 | 1354-6805 |
关键词 | Effort-reward imbalance schizotypal traits voxel-based morphometry resting-state functional connectivity |
DOI | 10.1080/13546805.2021.1899906 |
文献子类 | 实证研究 |
英文摘要 | Introduction Effort-reward imbalance (ERI) is a typical psychosocial stress. Schizotypal traits are attenuated features of schizophrenia in the general population. According to the diathesis-stress model, schizotypal traits and psychosocial stress contribute to the onset of schizophrenia. However, few studies examined the effects of these factors on brain alterations. This study aimed to examine relationships between ERI, schizotypal traits and brain structures and functions. Methods We recruited 37 (13 male, 24 female) participants with high levels of schizotypal traits and 36 (12 male, 24 female) participants with low levels of schizotypal traits by the Schizotypal Personality Questionnaire (SPQ). The Chinese school version of the effort-reward imbalance questionnaire (C-ERI-S) was used to measure ERI. We conducted the voxel-based morphometry (VBM) and whole brain resting-state functional connectivity (rsFC) analysis using reward or stress-related regions as seeds. Results Participants with high levels of schizotypal traits were more likely to perceive ERI. The severity of ERI was correlated with grey matter volume (GMV) reduction of the left pallidum and altered rsFC among the prefrontal, striatum and cerebellum in participants with high levels of schizotypal traits. Conclusion ERI is associated with GMV reduction and altered rsFC in individuals with high levels of schizotypal traits. |
资助项目 | National Key Research and Development Programme[2016YFC0906402] ; National Natural Science Foundation of China[31100747] ; Beijing Training Project for Leading Talents in ST[Z151100000315020] ; CAS Key Laboratory of Mental Health of Institute of Psychology |
WOS研究方向 | Psychiatry |
出版者 | ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD |
WOS记录号 | WOS:000628064000001 |
源URL | [http://ir.psych.ac.cn/handle/311026/38630] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Huang, Jia; Chan, Raymond C. K. |
作者单位 | 1.Tech Univ Denmark, Dept Appl Math & Comp Sci, Lyngby, Denmark 2.Castle Peak Hosp, Hong Kong, Peoples R China 3.Copenhagen Univ Hosp Hvidovre, Ctr Funct & Diagnost Imaging & Res, Danish Res Ctr Magnet Resonance, Hvidovre, Denmark 4.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 5.Sino Danish Ctr Educ & Res, Beijing, Peoples R China 6.Chinese Acad Sci, Sino Danish Coll, Beijing, Peoples R China 7.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing, Peoples R China 8.Univ Hong Kong, Dept Psychiat, Hong Kong, Peoples R China |
推荐引用方式 GB/T 7714 | Yan, Yong-jie,Huang, Jia,Lui, Simon S. Y.,et al. The effect of effort-reward imbalance on brain structure and resting-state functional connectivity in individuals with high levels of schizotypal traits[J]. COGNITIVE NEUROPSYCHIATRY,2021:17. |
APA | Yan, Yong-jie,Huang, Jia,Lui, Simon S. Y.,Cheung, Eric F. C.,Madsen, Kristoffer H.,&Chan, Raymond C. K..(2021).The effect of effort-reward imbalance on brain structure and resting-state functional connectivity in individuals with high levels of schizotypal traits.COGNITIVE NEUROPSYCHIATRY,17. |
MLA | Yan, Yong-jie,et al."The effect of effort-reward imbalance on brain structure and resting-state functional connectivity in individuals with high levels of schizotypal traits".COGNITIVE NEUROPSYCHIATRY (2021):17. |
入库方式: OAI收割
来源:心理研究所
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