Test-retest reliability of laser evoked pain perception and fMRI BOLD responses
文献类型:期刊论文
作者 | Bi, Yanzhi2,3; Hou, Xin2,3; Zhong, Jiahui1; Hu, Li2,3 |
刊名 | SCIENTIFIC REPORTS |
出版日期 | 2021-01-14 |
卷号 | 11期号:1页码:9 |
ISSN号 | 2045-2322 |
DOI | 10.1038/s41598-020-79196-z |
产权排序 | 1 |
文献子类 | 实证研究 |
英文摘要 | Pain perception is a subjective experience and highly variable across time. Brain responses evoked by nociceptive stimuli are highly associated with pain perception and also showed considerable variability. To date, the test-retest reliability of laser-evoked pain perception and its associated brain responses across sessions remain unclear. Here, an experiment with a within-subject repeated-measures design was performed in 22 healthy volunteers. Radiant-heat laser stimuli were delivered on subjects' left-hand dorsum in two sessions separated by 1-5 days. We observed that laser-evoked pain perception was significantly declined across sessions, coupled with decreased brain responses in the bilateral primary somatosensory cortex (S1), right primary motor cortex, supplementary motor area, and middle cingulate cortex. Intraclass correlation coefficients between the two sessions showed "fair" to "moderate" test-retest reliability for pain perception and brain responses. Additionally, we observed lower resting-state brain activity in the right S1 and lower resting-state functional connectivity between right S1 and dorsolateral prefrontal cortex in the second session than the first session. Altogether, being possibly influenced by changes of baseline mental state, laser-evoked pain perception and brain responses showed considerable across-session variability. This phenomenon should be considered when designing experiments for laboratory studies and evaluating pain abnormalities in clinical practice. |
资助项目 | National Natural Science Foundation of China[31800926] ; National Natural Science Foundation of China[32071061] ; National Natural Science Foundation of China[31822025] ; China Postdoctoral Science Foundation[2018M640191] ; Scientific Foundation of Institute of Psychology, Chinese Academy of Sciences[Y8CX351005] ; CAS Key Laboratory of Mental Health, Institute of Psychology[KLMH2018ZG01] ; Magnetic Resonance Imaging Research Center, Institute of Psychology, CAS |
WOS研究方向 | Science & Technology - Other Topics |
出版者 | NATURE RESEARCH |
WOS记录号 | WOS:000626774100036 |
源URL | [http://ir.psych.ac.cn/handle/311026/38755] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Hu, Li |
作者单位 | 1.Liaoning Normal Univ, Res Ctr Brain & Cognit Neurosci, Dalian 116029, Peoples R China 2.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing 100101, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing 100101, Peoples R China |
推荐引用方式 GB/T 7714 | Bi, Yanzhi,Hou, Xin,Zhong, Jiahui,et al. Test-retest reliability of laser evoked pain perception and fMRI BOLD responses[J]. SCIENTIFIC REPORTS,2021,11(1):9. |
APA | Bi, Yanzhi,Hou, Xin,Zhong, Jiahui,&Hu, Li.(2021).Test-retest reliability of laser evoked pain perception and fMRI BOLD responses.SCIENTIFIC REPORTS,11(1),9. |
MLA | Bi, Yanzhi,et al."Test-retest reliability of laser evoked pain perception and fMRI BOLD responses".SCIENTIFIC REPORTS 11.1(2021):9. |
入库方式: OAI收割
来源:心理研究所
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