Oxytocin modulates human chemosensory decoding of sex in a dose-dependent manner
文献类型:期刊论文
作者 | Chen, Kepu2; Ye, Yuting1; Troje, Nikolaus F.3; Zhou, Wen1,2,4 |
刊名 | ELIFE |
出版日期 | 2021-01-13 |
卷号 | 10页码:18 |
ISSN号 | 2050-084X |
DOI | 10.7554/eLife.59376 |
产权排序 | 4 |
文献子类 | 实证研究 |
英文摘要 | There has been accumulating evidence of human social chemo-signaling, but the underlying mechanisms remain poorly understood. Considering the evolutionarily conserved roles of oxytocin and vasopressin in reproductive and social behaviors, we examined whether the two neuropeptides are involved in the subconscious processing of androsta-4,16,-dien-3-one and estra-1,3,5 (10),16-tetraen-3-ol, two human chemosignals that convey masculinity and femininity to the targeted recipients, respectively. Psychophysical data collected from 216 heterosexual and homosexual men across five experiments totaling 1056 testing sessions consistently showed that such chemosensory communications of masculinity and femininity were blocked by a competitive antagonist of both oxytocin and vasopressin receptors called atosiban, administered nasally. On the other hand, intranasal oxytocin, but not vasopressin, modulated the decoding of androstadienone and estratetraenol in manners that were dose-dependent, nonmonotonic, and contingent upon the recipients' social proficiency. Taken together, these findings establish a causal link between neuroendocrine factors and subconscious chemosensory communications of sex-specific information in humans. |
WOS关键词 | INDIVIDUAL-DIFFERENCES ; PUTATIVE PHEROMONES ; SOCIAL RECOGNITION ; BRAIN RESPONSE ; HORMONE ; CHEMOSIGNALS ; INTRANASAL ; AUTISM ; VASOPRESSIN ; PLASMA |
资助项目 | National Natural Science Foundation of China[31830037] ; National Natural Science Foundation of China[31422023] ; National Natural Science Foundation of China[QYZDB-SSW-SMC055] ; National Natural Science Foundation of China[XDB32010200] |
WOS研究方向 | Life Sciences & Biomedicine - Other Topics |
语种 | 英语 |
出版者 | ELIFE SCIENCES PUBLICATIONS LTD |
WOS记录号 | WOS:000610884200001 |
源URL | [http://ir.psych.ac.cn/handle/311026/38477] |
专题 | 心理研究所_脑与认知科学国家重点实验室 |
通讯作者 | Zhou, Wen |
作者单位 | 1.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 2.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Inst Psychol, State Key Lab Brain & Cognit Sci, Beijing, Peoples R China 3.York Univ, Ctr Vis Res, Toronto, ON, Canada 4.Chinese Inst Brain Res, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Chen, Kepu,Ye, Yuting,Troje, Nikolaus F.,et al. Oxytocin modulates human chemosensory decoding of sex in a dose-dependent manner[J]. ELIFE,2021,10:18. |
APA | Chen, Kepu,Ye, Yuting,Troje, Nikolaus F.,&Zhou, Wen.(2021).Oxytocin modulates human chemosensory decoding of sex in a dose-dependent manner.ELIFE,10,18. |
MLA | Chen, Kepu,et al."Oxytocin modulates human chemosensory decoding of sex in a dose-dependent manner".ELIFE 10(2021):18. |
入库方式: OAI收割
来源:心理研究所
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