中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A guide to sample delivery systems for serial crystallography

文献类型:期刊论文

作者Zhao, FZ; Zhang, B; Yan, EK; Sun, B; Wang, ZJ; He, JH; Yin, DC
刊名FEBS JOURNAL
出版日期2019
卷号286期号:22页码:4402-4417
ISSN号1742-464X
关键词X-RAY-DIFFRACTION ROOM-TEMPERATURE FEMTOSECOND CRYSTALLOGRAPHY PROTEIN CRYSTALLIZATION STRUCTURAL BIOLOGY MILLISECOND CRYSTALLOGRAPHY CRYSTAL-STRUCTURE RADIATION-DAMAGE DATA-COLLECTION MICROCRYSTALS
DOI10.1111/febs.15099
文献子类期刊论文
英文摘要Crystallography has made a notable contribution to our knowledge of structural biology. For traditional crystallography experiments, the growth of crystals with large size and high quality is crucial, and it remains one of the bottlenecks. In recent years, the successful application of serial femtosecond crystallography (SFX) provides a new choice when only numerous microcrystals can be obtained. The intense pulsed radiation of X-ray free-electron lasers (XFELs) enables the data collection of small-sized crystals, making the size of crystals no longer a limiting factor. The ultrafast pulses of XFELs can achieve 'diffraction before destruction', which effectively avoids radiation damage and realizes diffraction near physiological temperatures. More recently, the SFX has been expanded to serial crystallography (SX) that can additionally employ synchrotron radiation as the light source. In addition to the traditional ones, these techniques provide complementary opportunities for structural determination. The development of SX experiments strongly relies on the advancement of hardware including the sample delivery system, the X-ray source, and the X-ray detector. Here, in this review, we categorize the existing sample delivery systems, summarize their progress, and propose their future prospectives.
语种英语
源URL[http://ir.sinap.ac.cn/handle/331007/31945]  
专题上海应用物理研究所_中科院上海应用物理研究所2011-2017年
作者单位1.Northwestern Polytech Univ, Shenzhen Res Inst, Shenzhen, Peoples R China
2.Northwestern Polytech Univ, Sch Life Sci, 127 West Youyi Rd, Xian 710072, Shaanxi, Peoples R China;
3.Chinese Acad Sci, Shanghai Inst Appl Phys, 239 Zhangheng Rd, Shanghai 201204, Peoples R China;
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GB/T 7714
Zhao, FZ,Zhang, B,Yan, EK,et al. A guide to sample delivery systems for serial crystallography[J]. FEBS JOURNAL,2019,286(22):4402-4417.
APA Zhao, FZ.,Zhang, B.,Yan, EK.,Sun, B.,Wang, ZJ.,...&Yin, DC.(2019).A guide to sample delivery systems for serial crystallography.FEBS JOURNAL,286(22),4402-4417.
MLA Zhao, FZ,et al."A guide to sample delivery systems for serial crystallography".FEBS JOURNAL 286.22(2019):4402-4417.

入库方式: OAI收割

来源:上海应用物理研究所

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