Acid-stimulated bioassembly of high-performance quantum dots in Escherichia coli
文献类型：期刊论文
| 作者 | Tian, LJ; Li, WW; Zhu, TT; Zhao, GH; Liu, XW; Dong, JC; An, PF; Ma, JY; Shen, F; Qian, C |
| 刊名 | JOURNAL OF MATERIALS CHEMISTRY A
 |
| 出版日期 | 2019 |
| 卷号 | 7期号:31页码:18480-18487 |
| 关键词 | BIOSYNTHESIS PH NANOPARTICLES NANOCRYSTALS TOXICITY CADMIUM |
| ISSN号 | 2050-7488 |
| DOI | 10.1039/c9ta06136c |
| 文献子类 | 期刊论文 |
| 英文摘要 | Biogenic quantum dots (Bio-QDs) with good luminescence properties and inherent biocompatibility are highly desirable for life science studies and hybrid solar-to-chemical production applications, but controlled bio-assembly is still challenging. Here, we report a facile and effective acid stimulation strategy that enables drastically enhanced production of CdSxSe1-x Bio-QDs in Escherichia coli. Lowering the pH from 7.5 to 4.5 resulted in a 25-fold higher Bio-QDs yield within 3.5 hours and significantly improved the Bio-QDs' fluorescence lifetime (133 ns) and quantum yield (7.3%) to a level far greater than those of the existing Bio-QDs. The enhanced Bio-QD production was associated with an increased production of reduced thiols in response to acid stress that trigger reactive oxygen species generation. The abundant reduced thiols in turn stimulated the uptake and transformation of Cd and Se into Bio-QDs. The resulting Bio-QDs, with uniform size (3.3 +/- 0.2 nm), outstanding fluorescence properties and high biocompatibility, showed good performance for non-destructive bioimaging of zebrafish in vivo. Our work opens a facile and generally applicable avenue for boosting Bio-QD assembly by imposing appropriate environmental stress, which may bring Bio-QDs a step closer to practical application. |
| 语种 | 英语 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/31957]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Univ Sci & Technol China, Sch Life Sci, CAS Key Lab Brain Funct & Dis, Hefei, Anhui, Peoples R China 2.Tongji Univ, Dept Chem, Shanghai Key Lab Chem Assessment & Sustainabil, Shanghai 200092, Peoples R China; 3.Univ Sci & Technol China, Dept Appl Chem, CAS Key Lab Urban Pollutant Convers, Hefei 230026, Anhui, Peoples R China; 4.Chinese Acad Sci, Inst High Energy Phys, Beijing Synchrotron Radiat Lab, Beijing 100049, Peoples R China; 5.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai Synchrotron Radiat Facil, Shanghai 201204, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Tian, LJ,Li, WW,Zhu, TT,et al. Acid-stimulated bioassembly of high-performance quantum dots in Escherichia coli[J]. JOURNAL OF MATERIALS CHEMISTRY A,2019,7(31):18480-18487. |
| APA | Tian, LJ.,Li, WW.,Zhu, TT.,Zhao, GH.,Liu, XW.,...&Yu, HQ.(2019).Acid-stimulated bioassembly of high-performance quantum dots in Escherichia coli.JOURNAL OF MATERIALS CHEMISTRY A,7(31),18480-18487. |
| MLA | Tian, LJ,et al."Acid-stimulated bioassembly of high-performance quantum dots in Escherichia coli".JOURNAL OF MATERIALS CHEMISTRY A 7.31(2019):18480-18487. |
入库方式： OAI收割
来源：上海应用物理研究所
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