Construction of pH-Triggered DNA Hydrogels Based on Hybridization Chain Reactions
文献类型：期刊论文
| 作者 | Li, YJ; Chen, J; Dong, YC; Liu, HJ; Liu, DS |
| 刊名 | CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
 |
| 出版日期 | 2019 |
| 页码 | - |
| 关键词 | NANOSTRUCTURES DESIGN TARGET |
| ISSN号 | 1005-9040 |
| DOI | 10.1007/s40242-019-0034-1 |
| 文献子类 | 期刊论文 |
| 英文摘要 | As a novel type of bio-functional material, DNA hydrogels have attracted more and more attention due to their successful applications in 3D cell culturing and tissue engineering for the designable and programmable responsiveness. Herein, we have developed a pH-triggered DNA hydrogel based on a clamped hybridization chain reaction(C-HCR). In this system, a DNA switch was designed, which can release the initiator strand in a controllable way via the formation of the C-G center dot C+ triplex under the pH stimuli. While the pre-gelation solution is stable in neutral environment, the C-HCR will trigger the sol-gel transition as the pH decreased to 5.0. This strategy has endowed the DNA hydrogel with good controllability for triggering, which also shows potential in intellectual responsiveness to certain stimuli. |
| 语种 | 英语 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/32009]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Tsinghua Univ, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Dept Chem, Beijing 100084, Peoples R China; 2.Tongji Univ, Sch Chem Sci & Engn, Shanghai Res Inst Intelligent Autonomous Syst, Key Lab Adv Civil Engn Mat,Minist Educ, Shanghai 200092, Peoples R China; 3.Chinese Acad Sci, CAS Key Lab Interfacial Phys & Technol, Shanghai Inst Appl Phys, Div Phys Biol, Shanghai 201800, Peoples R China; 4.Chinese Acad Sci, CAS Key Lab Colloid Interface & Chem Thermodynam, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, YJ,Chen, J,Dong, YC,et al. Construction of pH-Triggered DNA Hydrogels Based on Hybridization Chain Reactions[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2019:-. |
| APA | Li, YJ,Chen, J,Dong, YC,Liu, HJ,&Liu, DS.(2019).Construction of pH-Triggered DNA Hydrogels Based on Hybridization Chain Reactions.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,-. |
| MLA | Li, YJ,et al."Construction of pH-Triggered DNA Hydrogels Based on Hybridization Chain Reactions".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES (2019):-. |
入库方式： OAI收割
来源：上海应用物理研究所
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