Mechanical Properties of Sub-Microbubbles with a Nanoparticle-Decorated Polymer Shell
文献类型：期刊论文
| 作者 | Chu, XX; Tang, J; Geng, ZL; Wang, XY; Huo, GY; Zhou, LM; Wang, J; Yuan, KW; Yang, XD; Hu, J |
| 刊名 | LANGMUIR
 |
| 出版日期 | 2019 |
| 卷号 | 35期号:52页码:17090-17095 |
| 关键词 | FORCE MICROSPHERES COMPRESSION NANOBUBBLES |
| ISSN号 | 0743-7463 |
| DOI | 10.1021/acs.langmuir.9b02930 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Nanoparticle-decorated polymer-coated sub-microbubbles (NP-P-coated SMBs), as proved, have shown promising application prospects in ultrasound imaging, magnetic resonance imaging, drug delivery, and so forth. However, the quantitative evaluation of the stability and GAS mechanical properties of single NP-P-coated SMB is absent. Here, we first reported the stiffness and Young's modulus of single NP-P-coated SMB obtained by the PeakForce mode of atomic force microscopy. Such NP-P-coated SMBs could maintain perfect spherical shapes and have a thinner shell thickness (about 10 nm), as determined by characterization using a transmission electron microscope. Young's modulus of NP-P-coated SMBs is about 4.6 +/- 1.2 GPa, and their stiffness is about 15.0 +/- 3.1 N/m. Both modulus and stiffness are obtained from the linear region in the force-deformation curve and are nearly independent of their sizes. These results should be very useful to evaluate their stability, which plays a key role in maintaining the shell drug loading and acoustic capabilities. |
| 语种 | 英语 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/32130]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Ningbo Univ, Ningbo 315211, Zhejiang, Peoples R China; 2.Chinese Acad Sci, Shanghai Adv Res Inst, Shanghai Synchrotron Radiat Facil, Shanghai 201204, Peoples R China; 3.Southeast Univ, Sch Biol Sci & Med Engn, State Key Lab Bioelect, Jiangsu Key Lab Biomat & Devices, Nanjing 210096, Jiangsu, Peoples R China; 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 5.Chinese Acad Sci, Shanghai Inst Appl Phys, Key Lab Interfacial Phys & Technol, Shanghai 201800, Peoples R China; 6.Shanghai Tech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chu, XX,Tang, J,Geng, ZL,et al. Mechanical Properties of Sub-Microbubbles with a Nanoparticle-Decorated Polymer Shell[J]. LANGMUIR,2019,35(52):17090-17095. |
| APA | Chu, XX.,Tang, J.,Geng, ZL.,Wang, XY.,Huo, GY.,...&Zhang, LJ.(2019).Mechanical Properties of Sub-Microbubbles with a Nanoparticle-Decorated Polymer Shell.LANGMUIR,35(52),17090-17095. |
| MLA | Chu, XX,et al."Mechanical Properties of Sub-Microbubbles with a Nanoparticle-Decorated Polymer Shell".LANGMUIR 35.52(2019):17090-17095. |
入库方式： OAI收割
来源：上海应用物理研究所
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