Roles of Endovascular Calyx Related Enzymes in Endothelial Dysfunction and Diabetic Vascular Complications
文献类型：期刊论文
| 作者 | Li, Zhi1,2,3; Wu, Ning1,3,4; Wang, Jing1,2,3 ; Zhang, Quanbin1,2,3
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| 刊名 | FRONTIERS IN PHARMACOLOGY
 |
| 出版日期 | 2020-11-30 |
| 卷号 | 11页码:13 |
| ISSN号 | 1663-9812 |
| 关键词 | glycocalyx vascular complications diabetes endothelial dysfunction enzyme |
| DOI | 10.3389/fphar.2020.590614 |
| 通讯作者 | Wu, Ning(wuning@qdio.ac.cn) |
| 英文摘要 | In recent years, the number of diabetic patients has rapidly increased. Diabetic vascular complications seriously affect people's quality of life. Studies found that endothelial dysfunction precedes the vascular complications of diabetes. Endothelial dysfunction is related to glycocalyx degradation on the surface of blood vessels. Heparanase (HPSE), matrix metalloproteinase (MMP), hyaluronidase (HYAL), hyaluronic acid synthase (HAS), and neuraminidase (NEU) are related to glycocalyx degradation. Therefore, we reviewed the relationship between endothelial dysfunction and the vascular complications of diabetes from the perspective of enzymes. |
| 资助项目 | Science and Technology Service Network Initiative[KFJ-STS-QYZD-195] ; Shandong Province major science and technology innovation project[2019JZZY010818] ; Special Open Fund of Laboratory for Marine Biology and Biotechnology, Qingdao Pilot National Laboratory for Marine Science and Technology[OF2020NO02] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | FRONTIERS MEDIA SA |
| WOS记录号 | WOS:000598152000001 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/169371]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Wu, Ning |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 4.Pilot Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Zhi,Wu, Ning,Wang, Jing,et al. Roles of Endovascular Calyx Related Enzymes in Endothelial Dysfunction and Diabetic Vascular Complications[J]. FRONTIERS IN PHARMACOLOGY,2020,11:13. |
| APA | Li, Zhi,Wu, Ning,Wang, Jing,&Zhang, Quanbin.(2020).Roles of Endovascular Calyx Related Enzymes in Endothelial Dysfunction and Diabetic Vascular Complications.FRONTIERS IN PHARMACOLOGY,11,13. |
| MLA | Li, Zhi,et al."Roles of Endovascular Calyx Related Enzymes in Endothelial Dysfunction and Diabetic Vascular Complications".FRONTIERS IN PHARMACOLOGY 11(2020):13. |
入库方式： OAI收割
来源：海洋研究所
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