Review: Advances in preparation of chitooligosaccharides with heterogeneous sequences and their bioactivity
文献类型：期刊论文
| 作者 | Hao, Wentong1,2,3; Li, Kecheng1,2; Li, Pengcheng1,2
|
| 刊名 | CARBOHYDRATE POLYMERS
 |
| 出版日期 | 2021-01-15 |
| 卷号 | 252页码:11 |
| ISSN号 | 0144-8617 |
| 关键词 | Chitooligosaccharides Heterogeneous sequences Chitin deacetylases Synthesis Preparation |
| DOI | 10.1016/j.carbpol.2020.117206 |
| 通讯作者 | Li, Kecheng(lkc@qdio.ac.cn) ; Li, Pengcheng(pcli@qdio.ac.cn) |
| 英文摘要 | Chitooligosaccharides has attracted increasing attention due to their diverse bioactivities and potential application. Previous studies on the bioactivity of chitooligosaccharides were mostly carried out using a mixture. The structure-function relationship of chitooligosaccharides is not clear. Recently, it is confirmed that chitooligosaccharides with different degrees of polymerization play different roles in many bioactivities. However, heterogeneous chitooligosaccharides with a single degree of polymerization is still a mixture of many uncertain sequences and it is difficult to determine which structure is responsible for biological effects. Therefore, an interesting and challenging field of studying chitooligosaccharides with heterogeneous sequences has emerged. Herein, we reviewed the current methods for preparing heterogeneous chitooligosaccharides, including chemical synthesis, separation techniques and enzymatic methods. Advances in the bioactivities of chitooligosaccharides with heterogeneous sequences are also reviewed. |
| 资助项目 | National Natural Science Foundation of China[41976096,41406086] ; National Key R&D Program of China[2018YFC0311305,2019YFD0902105] ; Key Research and Development Program of Shandong Province[2019YYSP028] |
| WOS研究方向 | Chemistry ; Polymer Science |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCI LTD |
| WOS记录号 | WOS:000596865100002 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/169542]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Li, Kecheng; Li, Pengcheng |
| 作者单位 | 1.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hao, Wentong,Li, Kecheng,Li, Pengcheng. Review: Advances in preparation of chitooligosaccharides with heterogeneous sequences and their bioactivity[J]. CARBOHYDRATE POLYMERS,2021,252:11. |
| APA | Hao, Wentong,Li, Kecheng,&Li, Pengcheng.(2021).Review: Advances in preparation of chitooligosaccharides with heterogeneous sequences and their bioactivity.CARBOHYDRATE POLYMERS,252,11. |
| MLA | Hao, Wentong,et al."Review: Advances in preparation of chitooligosaccharides with heterogeneous sequences and their bioactivity".CARBOHYDRATE POLYMERS 252(2021):11. |
入库方式： OAI收割
来源：海洋研究所
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