Highlights of animal venom research on the geographical variations of toxin components, toxicities and envenomation therapy
文献类型：期刊论文
| 作者 | Yu, Chunlin2,3 ; Yu, Huahua1,2; Li, Pengcheng1,2
|
| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
 |
| 出版日期 | 2020-12-15 |
| 卷号 | 165页码:2994-3006 |
| 关键词 | Snake venom Jellyfish venom Scorpion venom Venom variation Geographical variation |
| ISSN号 | 0141-8130 |
| DOI | 10.1016/j.ijbiomac.2020.10.190 |
| 通讯作者 | Yu, Huahua(yuhuahua@qdio.ac.cn) |
| 英文摘要 | Geographical variation of animal venom is common among venomous animals. This kind of intraspecific variation based on geographical location mainly concerned from envenomation cases and brought new problems in animal venom studies, including venom components regulatory mechanisms, differentiation of venom activities, and clinical treatment methods. At present, food is considered as the most related factor influencing venom development. Related research defined the variational venomous animal species by the comparison of venom components and activities in snakes, jellyfish, scorpions, cone snails, ants, parasitoid wasps, spiders and toads. In snake venom studies, researchers found that antivenom effectiveness was variated to different located venom samples. As described in some snake venom research, developing region-specific antivenom is the development trend. The difficulties of developing region-specific antivenom and theoretical solutions have been discussed. This review summarized biological studies of animal venom geographical variation by species, compared venom components and major biological activities of the vary venom from the same species, and listed the basic methods in comparing venom protein compositions and major toxicity differences to provide a comprehensive reference. (c) 2020 Elsevier B.V. All rights reserved. |
| 资助项目 | National Natural Science Foundation of China[41776163] ; National Natural Science Foundation of China[41876164] ; National Key R&D Program of China[2019YFC0312605] ; National Key R&D Program of China[2017YFE0111100-04] ; Shandong Province Natural Science Foundation of China[ZR2019QD012] ; Qingdao Science and Technology Project[17-3-3-21-nsh] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000600773500129 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/169902]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Yu, Huahua |
| 作者单位 | 1.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Coll Earth & Planetary Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Chunlin,Yu, Huahua,Li, Pengcheng. Highlights of animal venom research on the geographical variations of toxin components, toxicities and envenomation therapy[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2020,165:2994-3006. |
| APA | Yu, Chunlin,Yu, Huahua,&Li, Pengcheng.(2020).Highlights of animal venom research on the geographical variations of toxin components, toxicities and envenomation therapy.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,165,2994-3006. |
| MLA | Yu, Chunlin,et al."Highlights of animal venom research on the geographical variations of toxin components, toxicities and envenomation therapy".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 165(2020):2994-3006. |
入库方式： OAI收割
来源：海洋研究所
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