The Effect of Pedal Peptide-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber Apostichopus japonicus
文献类型：期刊论文
| 作者 | Ding, Kui2,3,4,5 ; Zhang, Libin2,3,4,5,6,7; Fan, Xinhao2,3,4; Guo, Xueying2,3,4; Liu, Xiang2,3,4; Yang, Hongsheng1,2,3,4,5,6
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| 刊名 | FRONTIERS IN PHYSIOLOGY
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| 出版日期 | 2020-10-22 |
| 卷号 | 11页码:11 |
| 关键词 | echinoderm locomotor performance muscle metabolite pedal peptide neuropeptide |
| ISSN号 | 1664-042X |
| DOI | 10.3389/fphys.2020.559348 |
| 通讯作者 | Zhang, Libin(zhanglibin@qdio.ac.cn) |
| 英文摘要 | Neuropeptides are endogenous active substances that are present in nervous tissues and participate in behavioral and physiological processes of the animal system. Locomotor behavior is basic to predation, escape, reproduction in animals, and neuropeptides play an important role in locomotion. In this study, the function of pedal peptide-type neuropeptide (PDP) in the process of locomotor behavior of the sea cucumber Apostichopus japonicus was evaluated. The locomotor behavior of A. japonicus was recorded by infrared camera before and after PDP administration, and muscle physiology was studied by ultra performance liquid chromatography and quadrupole time-off-light mass spectrometry (UPLC-Q-TOF-MS) to clarify the potential physiological mechanisms. The results showed that PDP enhanced the cumulative duration of moving significantly at the 7th h after injection, and reduced the mean and maximum velocity by 16.90 and 14.22% in A. japonicus. The data of muscle metabolomics suggested that some significantly changed metabolites were related to locomotor behavior of sea cucumbers. The decreases of phosphatidylethanolamine (PE) and phosphatidylcholine (PC) might result in the increases of lysophosphatidylcholines (lysoPC) and lysophosphatidylethanolamine (lysoPE), and suggested the change of fluidity and permeability in the muscle cell membrane, which would affect the physiology and function of muscle cells, and finally alter the locomotor behavior. In addition, the increased level of arachidonic acid (ARA) might activate K+ ion channels and then affect the signaling of muscle cells, or promote the sensitivity of muscle cells to Ca2+ and then result in the contractility of longitudinal muscles in sea cucumbers. ARA was also involved in the linoleic acid metabolism which was the only pathway that disturbed significantly after PDP administration. In conclusion, PDP participated in the regulation of locomotor behavior in the sea cucumber, and the decreased PE and PC, increased lysoPC, lysoPE and ARA might be the potential physiological mechanisms that responsible for behavioral effects of PDP in A. japonicus. |
| 资助项目 | National Natural Science Foundation of China[41876157] ; National Natural Science Foundation of China[41676136] ; Key Deployment Project of Centre for Ocean Mega-Research of Science, Chinese Academy of Sciences[COMS2019Q15] ; STS Program of Chinese Academy of Sciences[KFJ-STS-ZDTP-077] ; Taishan Scholars Program (Distinguished Taishan Scholars) |
| WOS研究方向 | Physiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000585194800001 |
| 出版者 | FRONTIERS MEDIA SA |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/169138]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Zhang, Libin |
| 作者单位 | 1.Chinese Acad Sci, Innovat Acad Seed Design, Wuhan, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China 5.Chinese Acad Sci, Inst Oceanol, CAS Engn Lab Marine Ranching, Qingdao, Peoples R China 6.Univ Chinese Acad Sci, Beijing, Peoples R China 7.Minist Nat Resources, Inst Oceanog 2, State Key Lab Satellite Ocean Environm Dynam, Hangzhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, Kui,Zhang, Libin,Fan, Xinhao,et al. The Effect of Pedal Peptide-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber Apostichopus japonicus[J]. FRONTIERS IN PHYSIOLOGY,2020,11:11. |
| APA | Ding, Kui,Zhang, Libin,Fan, Xinhao,Guo, Xueying,Liu, Xiang,&Yang, Hongsheng.(2020).The Effect of Pedal Peptide-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber Apostichopus japonicus.FRONTIERS IN PHYSIOLOGY,11,11. |
| MLA | Ding, Kui,et al."The Effect of Pedal Peptide-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber Apostichopus japonicus".FRONTIERS IN PHYSIOLOGY 11(2020):11. |
入库方式： OAI收割
来源：海洋研究所
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