中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 自动化研究所
  3. 中国科学院自动化研究所
  4. 中国科学院分子影像重点实验室
A narrative review of near-infrared fluorescence imaging in hepatectomy for hepatocellular carcinoma

文献类型：期刊论文

作者Zhang, Weiqi4,5; Hu, Zhenhua3,4; Tian, Jie1,2,3,4; Fang, Chihua5
刊名ANNALS OF TRANSLATIONAL MEDICINE
出版日期2021
卷号9期号:2页码:15
关键词Near-infrared fluorescence imaging (NIRF imaging) fluorescent probe hepatectomy hepatocellular carcinoma (HCC) NIR-I NIR-II
ISSN号2305-5839
DOI10.21037/atm-20-5341
通讯作者Hu, Zhenhua(zhenhua.hu@ia.ac.cn) ; Tian, Jie(tian@ieee.org) ; Fang, Chihua(fangch_dr@163.com)
英文摘要Hepatectomy is a main therapeutic strategy for hepatocellular carcinoma (HCC), which requires removal of primary and disseminated tumors and maximum preservation of normal liver tissue. However, in a clinical operation, it is difficult to recognize the tumor tissue and its boundary with the naked eye and palpation, which often leads to insufficient or excessive resection. Near-infrared fluorescence (NIRF) imaging, a non-invasive, real-time, low-cost, and highly sensitive imaging technique has been extensively studied in surgical navigation. With the development of fluorescence imaging system and fluorescent probe, intraoperative tumor detection and margin definition can be achieved, making the operation more accurate. Advances in fluorescence imaging of HCC in the NIR region have focused on the traditional first NIR window (NIR-I, 700-900 nm), and have recently been extended to the second NIR window (NIR-II, 1,000- 1,700 nm). Compared with NIR-I imaging, fluorescence imaging in the NIR-II exhibits great advantages, including higher spatial resolution, deeper penetration depth, and lower optical absorption and scattering from biological substrates with minimal tissue autofluorescence. There is no doubt that developing novel NIRF probes for in vivo imaging of HCC has high significance and direct impact on the field of liver surgery. In this article, the development of various NIRF probes for fluorescence image guided HCC hepatectomy is reviewed, and current challenges and potential opportunities of these imaging probes are discussed.
WOS关键词CLINICAL-PRACTICE GUIDELINES ; INDOCYANINE-GREEN ; IN-VIVO ; PHOTOACOUSTIC TOMOGRAPHY ; NAVIGATION SYSTEM ; GUIDED SURGERY ; LIVER-TUMORS ; MANAGEMENT ; RESECTION ; LIGHT
资助项目National Key Research and Development Program of China[2016YFC0106500] ; National Key Research and Development Program of China[2016YFC0102600] ; National Key Research and Development Program of China[2017YFA0205200] ; National Natural Science Foundation of China (NSFC)[81627805] ; National Natural Science Foundation of China (NSFC)[81930053] ; National Natural Science Foundation of China (NSFC)[81671759] ; NSFC-GD Union Foundation, China[U1401254] ; National High Technology Research and Development Program of China (863 program)[2006AA02Z346] ; National High Technology Research and Development Program of China (863 program)[2012AA021105] ; Scientific Instrument Developing Project of the Chinese Academy of Sciences[YZ201672] ; Beijing Natural Science Foundation[JQ19027] ; Beijing Nova Program[Z181100006218046] ; innovative research team of high-level local universities in Shanghai
WOS研究方向Oncology ; Research & Experimental Medicine
语种英语
WOS记录号WOS:000617883200023
出版者AME PUBL CO
资助机构National Key Research and Development Program of China ; National Natural Science Foundation of China (NSFC) ; NSFC-GD Union Foundation, China ; National High Technology Research and Development Program of China (863 program) ; Scientific Instrument Developing Project of the Chinese Academy of Sciences ; Beijing Natural Science Foundation ; Beijing Nova Program ; innovative research team of high-level local universities in Shanghai
源URL[http://ir.ia.ac.cn/handle/173211/43356]  
专题自动化研究所_中国科学院分子影像重点实验室
通讯作者Hu, Zhenhua; Tian, Jie; Fang, Chihua
作者单位1.Beihang Univ, Beijing Adv Innovat Ctr Big Data Based Precis Med, Sch Med, Beijing, Peoples R China
2.Xidian Univ, Sch Life Sci & Technol, Minist Educ, Engn Res Ctr Mol & Neuro Imaging, Xian, Peoples R China
3.Univ Chinese Acad Sci, Beijing, Peoples R China
4.Chinese Acad Sci, State Key Lab Management & Control Complex Syst, Beijing Key Lab Mol Imaging, CAS Key Lab Mol Imaging,Inst Automat, Beijing, Peoples R China
5.Southern Med Univ, Guangdong Prov Clin & Engn Ctr Digital Med, Zhujiang Hosp, Dept Hepatobiliary Surg 1, Guangzhou, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Weiqi,Hu, Zhenhua,Tian, Jie,et al. A narrative review of near-infrared fluorescence imaging in hepatectomy for hepatocellular carcinoma[J]. ANNALS OF TRANSLATIONAL MEDICINE,2021,9(2):15.
APA Zhang, Weiqi,Hu, Zhenhua,Tian, Jie,&Fang, Chihua.(2021).A narrative review of near-infrared fluorescence imaging in hepatectomy for hepatocellular carcinoma.ANNALS OF TRANSLATIONAL MEDICINE,9(2),15.
MLA Zhang, Weiqi,et al."A narrative review of near-infrared fluorescence imaging in hepatectomy for hepatocellular carcinoma".ANNALS OF TRANSLATIONAL MEDICINE 9.2(2021):15.

入库方式： OAI收割

来源：自动化研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。