Functional Connectivity Predicts Individual Development of Inhibitory Control during Adolescence
文献类型:期刊论文
作者 | Wang, Haiyan27,28,29; Fan, Lingzhong27,28,29; Song, Ming27,28; Liu, Bing27,28,29,30; Wu, Dongya27,28,29; Jiang, Rongtao27,28,29; Li, Jin27,28; Li, Ang27,28,29; Banaschewski, Tobias17; Bokde, Arun L. W.18,19 |
刊名 | CEREBRAL CORTEX |
出版日期 | 2021-05-01 |
卷号 | 31期号:5页码:2686-2700 |
ISSN号 | 1047-3211 |
关键词 | adolescence functional connectivity inhibitory control longitudinal prediction stop signal task |
DOI | 10.1093/cercor/bhaa383 |
英文摘要 | Derailment of inhibitory control (IC) underlies numerous psychiatric and behavioral disorders, many of which emerge during adolescence. Identifying reliable predictive biomarkers that place the adolescents at elevated risk for future IC deficits can help guide early interventions, yet the scarcity of longitudinal research has hindered the progress. Here, using a large-scale longitudinal dataset in which the same subjects performed a stop signal task during functional magnetic resonance imaging at ages 14 and 19, we tracked their IC development individually and tried to find the brain features predicting their development by constructing prediction models using 14-year-olds' functional connections within a network or between a pair of networks. The participants had distinct between-subject trajectories in their IC development. Of the candidate connections used for prediction, ventral attention-subcortical network interconnections could predict the individual development of IC and formed a prediction model that generalized to previously unseen individuals. Furthermore, we found that connectivity between these two networks was related to substance abuse problems, an IC-deficit related problematic behavior, within 5 years. Our study reveals individual differences in IC development from mid- to late-adolescence and highlights the importance of ventral attention-subcortical network interconnections in predicting future IC development and substance abuse in adolescents. |
WOS关键词 | RESPONSE-INHIBITION ; ANTERIOR CINGULATE ; COGNITIVE CONTROL ; BRAIN ACTIVATION ; CONTROL NETWORKS ; CHILDHOOD ; DISORDERS ; RECRUITMENT ; IMPULSIVITY ; MATURATION |
资助项目 | National Key Research and Development Program of China[2017YFB1002502] ; National Key Research and Development Program of China[2017YFA0105203] ; Natural Science Foundation of China[91432302] ; Natural Science Foundation of China[31620103905] ; Natural Science Foundation of China[81501179] ; Science Frontier Program of the Chinese Academy of Sciences[QYZDJ-SSWSMC019] ; Beijing Brain Initiative of the BeijingMunicipal Science & Technology Commission[Z161100000216152] ; Beijing Brain Initiative of the BeijingMunicipal Science & Technology Commission[Z161100000216139] ; Beijing Brain Initiative of the BeijingMunicipal Science & Technology Commission[Z171100000117002] ; Beijing Brain Initiative of the BeijingMunicipal Science & Technology Commission[Z181100001518003] ; Beijing Brain Initiative of the BeijingMunicipal Science & Technology Commission[Z181100001518004] ; Guangdong Pearl River Talents Plan[2016ZT06S220] ; Youth Innovation Promotion Association ; Beijing Advanced Discipline Fund ; European Union[LSHM-CT-2007-037286] ; Horizon 2020[695313] ; ERANID (Understanding the Interplay between Cultural, Biological and Subjective Factors in Drug Use Pathways)[PR-ST0416-10004] ; BRIDGET (JPND: BRain Imaging, cognition Dementia and next generation GEnomics)[MR/N027558/1] ; Human Brain Project[785907] ; FP7 project MATRICS[603016] ; Medical Research Council Grant 'c-VEDA' (Consortium on Vulnerability to Externalizing Disorders and Addictions)[MR/N000390/1] ; National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London ; Bundesministeriumfur Bildung und Forschung (BMBF)[01GS08152] ; Bundesministeriumfur Bildung und Forschung (BMBF)[01EV0711] ; Bundesministeriumfur Bildung und Forschung (Forschungsnetz AERIAL)[01EE1406A] ; Bundesministeriumfur Bildung und Forschung (Forschungsnetz AERIAL)[01EE1406B] ; Deutsche Forschungsgemeinschaft (DFG)[SM 80/7-2] ; Deutsche Forschungsgemeinschaft (DFG)[SFB 940] ; Deutsche Forschungsgemeinschaft (DFG)[TRR 265] ; Deutsche Forschungsgemeinschaft (DFG)[NE 1383/14-1] ; Medical Research Foundation ; Medical Research Council[MR/R00465X/1] ; Medical Research Council[MR/S020306/1] ; National Institutes of Health (NIH)[5U54EB020403-05] ; National Institutes of Health (NIH)[1R56AG058854-01] ; ANR[ANR-12-SAMA-0004] ; ANR[AAPG2019-GeBra] ; Eranet Neuron[AF12-NEUR0008-01-WM2NA] ; Eranet Neuron[ANR-18NEUR00002-01-ADORe] ; Fondation de France[00081242] ; Fondation pour la Recherche Medicale[DPA20140629802] ; Mission Interministerielle de Lutte-contre-les-Drogues-etles-Conduites-Addictives (MILDECA) ; Assistance-PubliqueHopitaux-de-Paris ; INSERM (interface grant) ; Paris Sud University IDEX 2012 ; Fondation de l'Avenir[APRM-17-013] ; Federation pour la Recherche sur le Cerveau ; Science Foundation Ireland[16/ERCD/3797] ; USA (Axon, Testosterone and Mental Health during Adolescence)[RO1 MH085772-01A1] ; NIH[U54 EB020403] ; cross-NIH alliance that funds Big Data to Knowledge Centres of Excellence ; National Institutes of Health |
WOS研究方向 | Neurosciences & Neurology |
语种 | 英语 |
出版者 | OXFORD UNIV PRESS INC |
WOS记录号 | WOS:000642298300026 |
资助机构 | National Key Research and Development Program of China ; Natural Science Foundation of China ; Science Frontier Program of the Chinese Academy of Sciences ; Beijing Brain Initiative of the BeijingMunicipal Science & Technology Commission ; Guangdong Pearl River Talents Plan ; Youth Innovation Promotion Association ; Beijing Advanced Discipline Fund ; European Union ; Horizon 2020 ; ERANID (Understanding the Interplay between Cultural, Biological and Subjective Factors in Drug Use Pathways) ; BRIDGET (JPND: BRain Imaging, cognition Dementia and next generation GEnomics) ; Human Brain Project ; FP7 project MATRICS ; Medical Research Council Grant 'c-VEDA' (Consortium on Vulnerability to Externalizing Disorders and Addictions) ; National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London ; Bundesministeriumfur Bildung und Forschung (BMBF) ; Bundesministeriumfur Bildung und Forschung (Forschungsnetz AERIAL) ; Deutsche Forschungsgemeinschaft (DFG) ; Medical Research Foundation ; Medical Research Council ; National Institutes of Health (NIH) ; ANR ; Eranet Neuron ; Fondation de France ; Fondation pour la Recherche Medicale ; Mission Interministerielle de Lutte-contre-les-Drogues-etles-Conduites-Addictives (MILDECA) ; Assistance-PubliqueHopitaux-de-Paris ; INSERM (interface grant) ; Paris Sud University IDEX 2012 ; Fondation de l'Avenir ; Federation pour la Recherche sur le Cerveau ; Science Foundation Ireland ; USA (Axon, Testosterone and Mental Health during Adolescence) ; NIH ; cross-NIH alliance that funds Big Data to Knowledge Centres of Excellence ; National Institutes of Health |
源URL | [http://ir.ia.ac.cn/handle/173211/44651] |
专题 | 自动化研究所_脑网络组研究中心 |
通讯作者 | Schumann, Gunter; Jiang, Tianzi |
作者单位 | 1.Orsay Hosp, Psychiat Dept 91G16, Orsay, France 2.Univ Med Ctr Gottingen, Dept Child & Adolescent Psychiat & Psychotherapy, D-37075 Gottingen, Germany 3.Sorbonne Univ, Pitie Salpetriere Hosp, AP HP, Dept Child & Adolescent Psychiat, F-75013 Paris, France 4.Univ Nottingham, Sch Phys & Astron, Sir Peter Mansfield Imaging Ctr, Univ Pk, Nottingham NG7 2RD, England 5.Univ Paris 05, Univ Paris Sud, INSERM, U1000 Neuroimaging & Psychiat, F-75013 Paris, France 6.Univ Paris Saclay, INSERM, U1000 Neuroimaging & Psychiat, DIGITEO Labs,Univ Paris Sud, Rue Noetzlin, F-91190 Gif Sur Yvette, France 7.Univ Vermont, Dept Psychol, Burlington, VT 05405 USA 8.Univ Vermont, Dept Psychiat, Burlington, VT 05405 USA 9.Univ Paris Saclay, CEA, NeuroSpin, F-91191 Gif Sur Yvette, France 10.Charite Univ Med Berlin, Dept Psychiat & Psychotherapy CCM, Charitepl 1, D-10117 Berlin, Germany |
推荐引用方式 GB/T 7714 | Wang, Haiyan,Fan, Lingzhong,Song, Ming,et al. Functional Connectivity Predicts Individual Development of Inhibitory Control during Adolescence[J]. CEREBRAL CORTEX,2021,31(5):2686-2700. |
APA | Wang, Haiyan.,Fan, Lingzhong.,Song, Ming.,Liu, Bing.,Wu, Dongya.,...&Jiang, Tianzi.(2021).Functional Connectivity Predicts Individual Development of Inhibitory Control during Adolescence.CEREBRAL CORTEX,31(5),2686-2700. |
MLA | Wang, Haiyan,et al."Functional Connectivity Predicts Individual Development of Inhibitory Control during Adolescence".CEREBRAL CORTEX 31.5(2021):2686-2700. |
入库方式: OAI收割
来源:自动化研究所
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