ADHD Classification Within and Cross Cohort Using an Ensembled Feature Selection Framework
文献类型:会议论文
作者 | Yao DR(姚东任)![]() ![]() ![]() |
出版日期 | 2019 |
会议日期 | 2019/04/01 |
会议地点 | 意大利 |
英文摘要 |
Attention-deficit/hyperactivity disorder (ADHD) is a childhood-onset neurodevelopmental disorder that often persists into adulthood. However, as lacking objective measures, several studies have questioned the stability in diagnosing of ADHD from childhood to adulthood. In this study, we propose a novel feature selection framework based on functional connectivity (FCs) pattern, the so-called `FS_RIWEL,' which could classify ADHD from agematched healthy controls (HCs) with ~80% accuracy (both for children and adults). More importantly, the feature space learned from child ADHD dataset can discriminate adult ADHD from HCs at ~70% accuracy. To the best of our knowledge, this is the first attempt to perform a cross-cohort prediction between the adult and child ADHD using FC features. In addition, the most frequently selected FCs indicate that ADHD exhibit widely-impaired FC patterns in frontoparietal, basal ganglia, cerebellum network and so on suggesting that FCs may serve as potential biomarkers for ADHD diagnosis. |
语种 | 英语 |
源URL | [http://ir.ia.ac.cn/handle/173211/44782] ![]() |
专题 | 自动化研究所_脑网络组研究中心 |
通讯作者 | Sui J(隋婧) |
作者单位 | 1.Institute of Automation, Chinese Academy of Sciences 2.National Clinical Research Center for Mental Disorders & Key Laboratory of Mental Health, Ministry of Health, Peking University 3.The Mind Research Network, and Department of Electrical and Computer Engineering, University of New Mexico 4.University of Chinese Academy of Sciences |
推荐引用方式 GB/T 7714 | Yao DR,Sun HL,Guo XJ,et al. ADHD Classification Within and Cross Cohort Using an Ensembled Feature Selection Framework[C]. 见:. 意大利. 2019/04/01. |
入库方式: OAI收割
来源:自动化研究所
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