中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
ADHD Classification Within and Cross Cohort Using an Ensembled Feature Selection Framework

文献类型:会议论文

作者Yao DR(姚东任); Sun HL(孙海伦); Guo XJ(郭晓杰); Vince D. Calhoun; Sun L(孙黎); Sui J(隋婧)
出版日期2019
会议日期2019/04/01
会议地点意大利
英文摘要

 

Attention-deficit/hyperactivity disorder (ADHD) is a childhood-onset neurodevelopmental disorder that often persists into adulthood. However, as lacking objective measures, several studies have questioned the stability in diagnosing of ADHD from childhood to adulthood. In this study, we propose a novel feature selection framework based on functional connectivity (FCs) pattern, the so-called `FS_RIWEL,' which could classify ADHD from agematched healthy controls (HCs) with ~80% accuracy (both for children and adults). More importantly, the feature space learned from child ADHD dataset can discriminate adult ADHD from HCs at ~70% accuracy. To the best of our knowledge, this is the first attempt to perform a cross-cohort prediction between the adult and child ADHD using FC features. In addition, the most frequently selected FCs indicate that ADHD exhibit widely-impaired FC patterns in frontoparietal, basal ganglia, cerebellum network and so on suggesting that FCs may serve as potential biomarkers for ADHD diagnosis.

语种英语
源URL[http://ir.ia.ac.cn/handle/173211/44782]  
专题自动化研究所_脑网络组研究中心
通讯作者Sui J(隋婧)
作者单位1.Institute of Automation, Chinese Academy of Sciences
2.National Clinical Research Center for Mental Disorders & Key Laboratory of Mental Health, Ministry of Health, Peking University
3.The Mind Research Network, and Department of Electrical and Computer Engineering, University of New Mexico
4.University of Chinese Academy of Sciences
推荐引用方式
GB/T 7714
Yao DR,Sun HL,Guo XJ,et al. ADHD Classification Within and Cross Cohort Using an Ensembled Feature Selection Framework[C]. 见:. 意大利. 2019/04/01.

入库方式: OAI收割

来源:自动化研究所

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