Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate
文献类型：期刊论文
| 作者 | Yu Xiaoming3; Tan Lili3; Liu Zongyuan3; Yang Ke3; Zhu Zhonglin1; Li Yangde2 |
| 刊名 | ACTA METALLURGICA SINICA
 |
| 出版日期 | 2018-06-01 |
| 卷号 | 54期号:6页码:943-949 |
| 关键词 | Ti alloy pure Mg coating bioproperty |
| ISSN号 | 0412-1961 |
| DOI | 10.11900/0412.1961.2017.00285 |
| 通讯作者 | Tan Lili(lltan@imr.ac.cn) |
| 英文摘要 | Currently, metallic biomaterials used in orthopedics are normally bioinert which is hard to integrate with the bone tissue inducing aseptic loosening and easy to get infection, which is the main reason of implantation failure. Mg base metals are considered to be a new generation of revolutionary metallic biomaterials due to its similar density and mechanical properties with natural bone, good biocompatibility, degradability in the body as well as the biological functional ability to promote new bone tissue formation. In addition, the degradation of Mg may increase the local pH which can inhibit the growth of bacteria. In this work, pure Mg coating was deposited on Ti6Al4V substrate by arc ion plating. The effects of different working pressures on the surface quality and properties of Mg coating were investigated. The degradation, antibacterial and biosafety properties were studyied. The results showed that the pure Mg coating can be deposited on the surface of Ti6Al4V substrate and the coating was uniform and smooth. The immersion test in vitro showed that the degradation was very fast because of galvanic corrosion, and the whole process was finished in about one week. The results of antimicrobial experiments showed that the Mg coating can kill staphylococcus aureus and showed good antibacterial function. The results of cytotoxicity test showed that Mg coating promoted rabbit bone marrow mesenchymal stem cells (rBMSCs) growth and proliferation. |
| 资助项目 | National Natural Science Foundation of China[51631009] ; National Natural Science Foundation of China[81500897] ; National Natural Science Foundation of China[81400528] ; National Key Research and Development Program of China[2016YFC1101804] |
| WOS研究方向 | Metallurgy & Metallurgical Engineering |
| 语种 | 英语 |
| WOS记录号 | WOS:000433007400014 |
| 出版者 | SCIENCE PRESS |
| 资助机构 | National Natural Science Foundation of China ; National Key Research and Development Program of China |
| 源URL | [http://ir.imr.ac.cn/handle/321006/128468]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 通讯作者 | Tan Lili |
| 作者单位 | 1.Jiangsu OKANI Med Technol Co Ltd, Suzhou 215123, Peoples R China 2.Dong Guan EONTC Co Ltd, Dongguan 523808, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu Xiaoming,Tan Lili,Liu Zongyuan,et al. Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate[J]. ACTA METALLURGICA SINICA,2018,54(6):943-949. |
| APA | Yu Xiaoming,Tan Lili,Liu Zongyuan,Yang Ke,Zhu Zhonglin,&Li Yangde.(2018).Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate.ACTA METALLURGICA SINICA,54(6),943-949. |
| MLA | Yu Xiaoming,et al."Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate".ACTA METALLURGICA SINICA 54.6(2018):943-949. |
入库方式： OAI收割
来源：金属研究所
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