Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing
文献类型：期刊论文
| 作者 | Yan, Xudong2; Wan, Peng3; Tan, Lili2; Zhao, Mingchun1; Qin, Ling4; Yang, Ke2 |
| 刊名 | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
 |
| 出版日期 | 2018-12-01 |
| 卷号 | 93页码:565-581 |
| 关键词 | Magnesium alloy Copper Corrosion Processing Antibacterial |
| ISSN号 | 0928-4931 |
| DOI | 10.1016/j.msec.2018.08.013 |
| 通讯作者 | Wan, Peng(wanpeng@dgut.edu.cn) |
| 英文摘要 | Mg-Cu alloys were designed by introducing the well-known antibacterial property of copper into magnesium alloy to solve the infection problem especially under the neutralised environment in vitro. In this paper, the Mg-Cu alloys with further processing by solution and extrusion were studied to optimise the corrosion-related performance for their future application. It was shown that the differences in the property profile of Mg-Cu alloys are dependent on different compositions as well as on different microstructures that are obtained by the different processing routes. Galvanic corrosion can be significantly relieved by solution treatment and extrusion due to decrease and well distribution of cathodic Mg2Cu phases. Negligible cytotoxicity were observed with rBMSCs incubation. Antibacterial assays proved that the alloys reduced the viability of Staphylococcus aureus by high alkalinity and copper ions releasing, especially in comparison with pure magnesium. Finally, the as-solutionized Mg-0.1Cu alloy showed the optimal corrosion properties and promising antibacterial activity, which warranted its potentials as antibacterial biodegradable implant materials. |
| 资助项目 | National Natural Science Foundation of China[31500777] ; National Natural Science Foundation of China[51631009] ; National Natural Science Foundation of China[81501859] ; National High Technology Research and Development Program of China (863 Program)[2015AA033701] ; Hong Kong Scholar Program ; CAS-Crouctier Founding Scheme for Joint Laboratories[CAS14303] |
| WOS研究方向 | Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000447569400054 |
| 出版者 | ELSEVIER SCIENCE BV |
| 资助机构 | National Natural Science Foundation of China ; National High Technology Research and Development Program of China (863 Program) ; Hong Kong Scholar Program ; CAS-Crouctier Founding Scheme for Joint Laboratories |
| 源URL | [http://ir.imr.ac.cn/handle/321006/130011]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 通讯作者 | Wan, Peng |
| 作者单位 | 1.Cent S Univ, Sch Mat Sci & Engn, Changsha 410083, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 3.Dongguan Univ Technol, Sch Mech Engn, Dongguan 523808, Peoples R China 4.Chinese Univ Hong Kong, Li Ka Shing Inst Hlth Sci, Dept Orthopaed & Traumatol, Hong Kong, Hong Kong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yan, Xudong,Wan, Peng,Tan, Lili,et al. Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2018,93:565-581. |
| APA | Yan, Xudong,Wan, Peng,Tan, Lili,Zhao, Mingchun,Qin, Ling,&Yang, Ke.(2018).Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,93,565-581. |
| MLA | Yan, Xudong,et al."Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 93(2018):565-581. |
入库方式： OAI收割
来源：金属研究所
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