Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material
文献类型:期刊论文
作者 | Ma, Zheng1; Gao, Ming1,3; Na, Di4; Li, Yangde2; Tan, Lili1; Yang, Ke1 |
刊名 | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
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出版日期 | 2019-10-01 |
卷号 | 103页码:8 |
关键词 | Fe-Mn-C-Cu alloy Biodegradable Anti-infection Urinary implant material Anti-encrustation |
ISSN号 | 0928-4931 |
DOI | 10.1016/j.msec.2019.05.003 |
通讯作者 | Tan, Lili(lltan@imr.ac.cn) ; Yang, Ke(kyang@imr.ac.cn) |
英文摘要 | Biodegradable Fe based alloys have been investigated for fracture fixation and cardiovascular support to overcome complications of permanent implants. This study was focused on the development of a new Fe-Mn-CCu alloy with antibacterial and anti-encrustation properties as a urinary implant material. The microstructure and mechanical properties of the alloy were studied. The degradation behavior, antibacterial and anti-encrustation properties were evaluated by immersion test, antibacterial test and encrustation test, respectively. The results showed that Fe-Mn-C-Cu alloy was a non-magnetic, biodegradable, anti-bacterial and anti-encrustation alloy that could inhibit the biofilm and stone formations on its surface through the dual effects of degradation and Cu ions release. The study revealed the preliminary mechanisms of anti-infection and anti-encrustation for Fe-Mn-C-Cu alloy due to the continuous release of Cu2+ ions, which provides a new idea for application of biodegradable Fe-based material and the treatment of urinary tract infections and stones in the urinary system. |
资助项目 | Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1101804] ; Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1100604] ; Double Hundred Project Plan of Shenyang Key Scientific and Technological Achievements Transformation Project[Z18-0-027] |
WOS研究方向 | Materials Science |
语种 | 英语 |
WOS记录号 | WOS:000480664900021 |
出版者 | ELSEVIER |
资助机构 | Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement ; Double Hundred Project Plan of Shenyang Key Scientific and Technological Achievements Transformation Project |
源URL | [http://ir.imr.ac.cn/handle/321006/134995] ![]() |
专题 | 金属研究所_中国科学院金属研究所 |
通讯作者 | Tan, Lili; Yang, Ke |
作者单位 | 1.Chinese Acad Sci, Inst Met Res, Shenyang, Liaoning, Peoples R China 2.Dongguan Eontech Co Ltd, Dongguan 523662, Peoples R China 3.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang, Liaoning, Peoples R China 4.China Med Univ, Dept Surg Oncol, Affiliated Hosp 1, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Ma, Zheng,Gao, Ming,Na, Di,et al. Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2019,103:8. |
APA | Ma, Zheng,Gao, Ming,Na, Di,Li, Yangde,Tan, Lili,&Yang, Ke.(2019).Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,103,8. |
MLA | Ma, Zheng,et al."Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 103(2019):8. |
入库方式: OAI收割
来源:金属研究所
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