Determination of Total Arsenic and Arsenic Metabolites in Human Liver Hepatocytes
文献类型：期刊论文
| 作者 | Cao Xuan3; Yu JingJing4; Wang Geng5; Yu ZhenHua4; Yang HuangHao4; Xu YuanYuan2; Sun GuiFan2; Wang XiaoRu4 |
| 刊名 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2009 |
| 卷号 | 37期号:1页码:19-24 |
| 关键词 | INGESTION TOXICITY RATS ACID Cell digestion high performance liquid chromatography-inductively coupled plasma-mass sepetrometry Chang liver hepatocytes arsenic speciation |
| ISSN号 | 0253-3820 |
| 其他题名 | Determination of Total Arsenic and Arsenic Metabolites in Human Liver Hepatocytes |
| 英文摘要 | The effects of direct sampling and three digestion methods were investigated on the determination of arsenic in Chang liver hepatocytes after ultrasonic disintegration were investigated. The results showed that the efficiency of microwave digestion and obturator digestion was better than cold digestion and direct sampling. The day precision (present as RSD) of microwave digestion and obturator digestion were 2.1% and 1.2% the inter-day precision were 1.2% and 2.0%, respectively. The spike recovery for the total As in the sample is 95.7% - 108.1%. The As detection limits with these four sample treatment methods (including direct sampling) were 0.74 - 0.93 mu g/L. In addition, arsenic speciation in Chang liver hepatocytes was also analyzed using the hyphenated technique of high performance liquid chromatography coupled with inductively coupled plasma-mass spectrometry. The experimental results indicated that dimethylarsinic acid (DMA) and an intermediate metabolite of DMA were found lit Chang liver hepatocytes besides inorganic arsenic (As(III) and As(V)). |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3486776 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/142678]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.中国科学院 2.中国科学院金属研究所 3.陕西省地震局 4.黑龙江省环境保护科学研究院 5.山东大学 |
| 推荐引用方式 GB/T 7714 | Cao Xuan,Yu JingJing,Wang Geng,et al. Determination of Total Arsenic and Arsenic Metabolites in Human Liver Hepatocytes[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2009,37(1):19-24. |
| APA | Cao Xuan.,Yu JingJing.,Wang Geng.,Yu ZhenHua.,Yang HuangHao.,...&Wang XiaoRu.(2009).Determination of Total Arsenic and Arsenic Metabolites in Human Liver Hepatocytes.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,37(1),19-24. |
| MLA | Cao Xuan,et al."Determination of Total Arsenic and Arsenic Metabolites in Human Liver Hepatocytes".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 37.1(2009):19-24. |
入库方式： OAI收割
来源：金属研究所
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