Synthesis and Antiproliferative Activity of Novel 1,2,4Triazolo1,5-apyrimidine-7-amine Derivatives
文献类型：期刊论文
| 作者 | Zhai Xin; Zhang Cunlong; He Lei; Li Qi; Wang Jiuliang; Shen Xiaoli; Gong Ping |
| 刊名 | CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
 |
| 出版日期 | 2009 |
| 卷号 | 25期号:4页码:474-479 |
| 关键词 | INHIBITORS SAR 1,2,4Triazolo1,5-apyrimidines Antiproliferative activity Anticancer |
| ISSN号 | 1005-9040 |
| 其他题名 | Synthesis and Antiproliferative Activity of Novel 1,2,4Triazolo1,5-apyrimidine-7-amine Derivatives |
| 英文摘要 | A series of novel N-anilino-2-substituted-5-methyl-1,2,4triazolo1,5-apyrimidine-7-amine derivatives was prepared and evaluated for their in vitro antiproliferative activity against two cancer cell lines, Bel-7402 and HT-1080. Most of the compounds inhibited the cell proliferation at a low concentration. Seven compounds, VI(5), VI(7), VI(10), and VI(12)-VI(15). possessed marked antiproliferative activity superior to that of cisplatin. Of these seven initial hits, compound VI(10) was the most active. |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3684043 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/143487]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | Zhai Xin,Zhang Cunlong,He Lei,et al. Synthesis and Antiproliferative Activity of Novel 1,2,4Triazolo1,5-apyrimidine-7-amine Derivatives[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2009,25(4):474-479. |
| APA | Zhai Xin.,Zhang Cunlong.,He Lei.,Li Qi.,Wang Jiuliang.,...&Gong Ping.(2009).Synthesis and Antiproliferative Activity of Novel 1,2,4Triazolo1,5-apyrimidine-7-amine Derivatives.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,25(4),474-479. |
| MLA | Zhai Xin,et al."Synthesis and Antiproliferative Activity of Novel 1,2,4Triazolo1,5-apyrimidine-7-amine Derivatives".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 25.4(2009):474-479. |
入库方式： OAI收割
来源：金属研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。