Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKCa channels and reducing intracellular Ca2+ levels
文献类型：期刊论文
| 作者 | Gai Xiangyun1; Wei Yuhai3; Zhang Wei2; Wuren Tana2; Wang Yaping2; Li Zhanqiang2; Liu Shou2; Ma Lan2; Lu Dianxiang2; Zhou Yi1 |
| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 2015 |
| 卷号 | 36期号:5页码:587-596 |
| ISSN号 | 1671-4083 |
| 关键词 | ACTIVATED POTASSIUM CHANNELS K+ CHANNELS CALCIUM-CHANNEL Tibetan herb echinacoside pulmonary hypertension high altitude vasorelaxation NO BKCa K-IR artery ring pulmonary arterial smooth muscle cells |
| 其他题名 | Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BK Ca channels and reducing intracellular Ca 2+ levels |
| 英文摘要 | Aim: Sustained pulmonary vasoconstriction as experienced at high altitude can lead to pulmonary hypertension (PH). The main purpose of this study is to investigate the vasorelaxant effect of echinacoside (ECH), a phenylethanoid glycoside from the Tibetan herb Lagotis brevituba Maxim and Cistanche tubulosa, on the pulmonary artery and its potential mechanism. |
| 资助项目 | [National Program on Key Basic Research Project of China] ; [Program of International Science and Technology Cooperation of China] ; [National Natural Science Foundation of China] ; [Key Laboratories Development Program of Qinghai Province] ; [Qinghai-Utah Joint Research Key Lab for High Altitude Medicine] ; [Ministry of Education New Century Outstanding Talents Support Program of China] ; [Natural Science Foundation of Qinghai] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:5425432 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/143844]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.中国科学院金属研究所 2.青海大学 3.Qinghai Entry Exit Inspect & Quarantine Bur, Xining 810001, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gai Xiangyun,Wei Yuhai,Zhang Wei,et al. Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKCa channels and reducing intracellular Ca2+ levels[J]. ACTA PHARMACOLOGICA SINICA,2015,36(5):587-596. |
| APA | Gai Xiangyun.,Wei Yuhai.,Zhang Wei.,Wuren Tana.,Wang Yaping.,...&Ge Rili.(2015).Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKCa channels and reducing intracellular Ca2+ levels.ACTA PHARMACOLOGICA SINICA,36(5),587-596. |
| MLA | Gai Xiangyun,et al."Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKCa channels and reducing intracellular Ca2+ levels".ACTA PHARMACOLOGICA SINICA 36.5(2015):587-596. |
入库方式： OAI收割
来源：金属研究所
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