Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA
文献类型：期刊论文
| 作者 | Pan LeiTing2; Sun WenWu1; Qi JiWei2; Wu Xian2; Song Kun2; Hu Fen2; Zhang XinZheng2; Xu JingJun2 |
| 刊名 | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
 |
| 出版日期 | 2009 |
| 卷号 | 36期号:1页码:83-87 |
| ISSN号 | 1000-3282 |
| 关键词 | ATOMIC-FORCE MICROSCOPY PROTEIN-KINASE-C RHEUMATOID-ARTHRITIS CORTICAL CYTOSKELETON SYNOVIAL FIBROBLASTS ACTIN CYTOSKELETON CELLS ACTIVATION synoviocytes cytoskeleton PMA PKC atomic force microscopy |
| 其他题名 | Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA |
| 英文摘要 | Rat synoviocytes were cultured in vitro and the changing of cellular cytoskeleton induced by PMA was investigated with atomic force microscopy. PMA is usually used to stimulate PKC signal transduction pathway in synoviocytes and to simulate process of inflammation. The results presented here show that synoviocyte cytoskeleton has changed significantly after PKC activation by using the imaging of atomic force microscopy. The results also indicate that the activation of PKC might play crucial role in cytoskeleton changing of synoviocytes, which, to some extent, provides some experiments and ideas on understanding the mechanism underlying rheumatoid arthritis (RA). |
| 资助项目 | [National Basic Research Program of China] ; [Key International S&T Cooperation Project of China] ; [Programme of Introducing Talents of Displine to Universities] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3487928 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/144177]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.中国科学院金属研究所 2.南开大学 |
| 推荐引用方式 GB/T 7714 | Pan LeiTing,Sun WenWu,Qi JiWei,et al. Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2009,36(1):83-87. |
| APA | Pan LeiTing.,Sun WenWu.,Qi JiWei.,Wu Xian.,Song Kun.,...&Xu JingJun.(2009).Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,36(1),83-87. |
| MLA | Pan LeiTing,et al."Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 36.1(2009):83-87. |
入库方式： OAI收割
来源：金属研究所
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