Ureido-modification of the resin-bound LHRH analogue with N,N '-carbonyldiimidazole
文献类型:期刊论文
作者 | Gao Yong Qing1; Zhou Ning1; Lv Yu Jian1; Cheng Mao Sheng2; Liu Ke Liang1 |
刊名 | CHINESE CHEMICAL LETTERS
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出版日期 | 2009 |
卷号 | 20期号:6页码:668-671 |
关键词 | UREAS Urea moiety N,N'-carbonyldiimidazole (CDI) Solid-phase Peptide |
ISSN号 | 1001-8417 |
其他题名 | Ureido-modification of the resin-bound LHRH analogue with N,N′-carbonyldiimidazole |
英文摘要 | The ureido-modification of the resin-bound a luteinizing hormone releasing hormone (LHRH) analogue was investigated by CDI-activating method. The an-lino group at the side chain of LHRH analogue could be transformed into various substituted urea moieties in high yields. However, its terminal amino group was partially converted to a hydantoin structure due to the attack of the N atom of the adjacent amide bond. (C) 2009 Ke Liang Liu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
资助项目 | [National Natural Science Foundation of China] |
语种 | 英语 |
CSCD记录号 | CSCD:3757051 |
源URL | [http://ir.imr.ac.cn/handle/321006/144430] ![]() |
专题 | 金属研究所_中国科学院金属研究所 |
作者单位 | 1.Beijing Institute Pharmacol & Toxicol, Beijing 100850, Peoples R China 2.中国科学院金属研究所 |
推荐引用方式 GB/T 7714 | Gao Yong Qing,Zhou Ning,Lv Yu Jian,et al. Ureido-modification of the resin-bound LHRH analogue with N,N '-carbonyldiimidazole[J]. CHINESE CHEMICAL LETTERS,2009,20(6):668-671. |
APA | Gao Yong Qing,Zhou Ning,Lv Yu Jian,Cheng Mao Sheng,&Liu Ke Liang.(2009).Ureido-modification of the resin-bound LHRH analogue with N,N '-carbonyldiimidazole.CHINESE CHEMICAL LETTERS,20(6),668-671. |
MLA | Gao Yong Qing,et al."Ureido-modification of the resin-bound LHRH analogue with N,N '-carbonyldiimidazole".CHINESE CHEMICAL LETTERS 20.6(2009):668-671. |
入库方式: OAI收割
来源:金属研究所
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