Organocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines
文献类型:期刊论文
作者 | Yu Fang1; Zhang Xiaojing1; Jiang Yongwen2 |
刊名 | CHINESE JOURNAL OF CHEMISTRY
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出版日期 | 2011 |
卷号 | 29期号:9页码:1873-1879 |
关键词 | MICHAEL ADDITION 2,4-DISUBSTITUTED PIPERIDINES MULTICOMPONENT REACTIONS ALDEHYDES CYCLIZATION SCAFFOLDS ENTRY WATER organocatalysis Michael addition reductive amination substituted piperidine tetrahydropyridine |
ISSN号 | 1001-604X |
其他题名 | Organocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines |
英文摘要 | A convenient and highly enantioselective method for assembly of functionalized 1,2,3,4,5-pentasubstituted tetrahydropyridines and piperidines was developed. This method relies on preparing the required enantiopure cyclic semi-acetals via an organocatalyzed Michael addition/cyclization cascade reaction of aldehydes and alpha-keto-alpha,beta-unsaturated esters, and subsequent reductive amination/condensation with primary amines. |
资助项目 | [National Natural Science Foundation of China] |
语种 | 英语 |
CSCD记录号 | CSCD:4352577 |
源URL | [http://ir.imr.ac.cn/handle/321006/146209] ![]() |
专题 | 金属研究所_中国科学院金属研究所 |
作者单位 | 1.中国科学院金属研究所 2.中国科学院 |
推荐引用方式 GB/T 7714 | Yu Fang,Zhang Xiaojing,Jiang Yongwen. Organocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines[J]. CHINESE JOURNAL OF CHEMISTRY,2011,29(9):1873-1879. |
APA | Yu Fang,Zhang Xiaojing,&Jiang Yongwen.(2011).Organocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines.CHINESE JOURNAL OF CHEMISTRY,29(9),1873-1879. |
MLA | Yu Fang,et al."Organocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines".CHINESE JOURNAL OF CHEMISTRY 29.9(2011):1873-1879. |
入库方式: OAI收割
来源:金属研究所
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