中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Two new ursane-type nortriterpenes from Lonicera macranthoides and their iNOS-inhibitory activities

文献类型:期刊论文

作者Mei YuDan1; Zhang Nan3; Zhang WeiYang4; Tang JinShan1; Zhou Hua4; Yu Yang1; Yao XinSheng1
刊名CHINESE JOURNAL OF NATURAL MEDICINES
出版日期2019
卷号17期号:1页码:27-32
关键词TRITERPENOID SAPONINS GLYCOSIDES BUDS STEMS Lonicerae Flos Lonicera macranthoides Ursane-type nortriterpenes Anti-inflammation iNOS
ISSN号2095-6975
英文摘要The flower buds of Lonicera macranthoides (Shan Yin-Hua), represent an important traditional Chinese medicine and food ingredient. A phytochemical investigation of the 70% EtOH extract of the flower buds of L. macranthoides resulted in the isolation of 12 triterpenoids (1-12), including two new ursane-type nortriterpenes, 2 alpha, 24-dihydroxy-23-nor-ursolic acid (1) and 2 alpha, 4 alpha-dihydroxy-23-nor-ursolic acid (2). Their structures were established by multiple spectroscopic methods and comparison with literature data. All isolated compounds were evaluated for their anti-inflammatory effects in LPS-activated RAW264.7 cells. Compounds 1 and 2 exhibited inhibitory effects on iNOS at the concentration of 30 mu mol.L-1.
资助项目[National Natural Science Foundation of China] ; [Science and Technology Planning Project of Guangdong Province]
语种英语
CSCD记录号CSCD:6416308
源URL[http://ir.imr.ac.cn/handle/321006/146389]  
专题金属研究所_中国科学院金属研究所
作者单位1.中国科学院广州地球化学研究所
2.暨南大学
3.中国科学院金属研究所
4.Macau University Sci & Technol, Fac Chinese Med, Macau 999078, Peoples R China Fac Chinese Med
5.Macau University Sci & Technol, State Key Lab Qual Res Chinese Med, Macau 999078, Peoples R China State Key Lab Qual Res Chinese Med
推荐引用方式
GB/T 7714
Mei YuDan,Zhang Nan,Zhang WeiYang,et al. Two new ursane-type nortriterpenes from Lonicera macranthoides and their iNOS-inhibitory activities[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2019,17(1):27-32.
APA Mei YuDan.,Zhang Nan.,Zhang WeiYang.,Tang JinShan.,Zhou Hua.,...&Yao XinSheng.(2019).Two new ursane-type nortriterpenes from Lonicera macranthoides and their iNOS-inhibitory activities.CHINESE JOURNAL OF NATURAL MEDICINES,17(1),27-32.
MLA Mei YuDan,et al."Two new ursane-type nortriterpenes from Lonicera macranthoides and their iNOS-inhibitory activities".CHINESE JOURNAL OF NATURAL MEDICINES 17.1(2019):27-32.

入库方式: OAI收割

来源:金属研究所

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。