Synthesis and biological evaluation of novel tricyclic oximino derivatives as antitumor agents
文献类型：期刊论文
| 作者 | Guo Shuchun; Zhao Yanfang; Li Rongdong; Xie Lijun; Yang Youbin; Gong Ping |
| 刊名 | CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
 |
| 出版日期 | 2008 |
| 卷号 | 24期号:1页码:47-53 |
| 关键词 | ANTITUBULIN AGENTS DESIGN thieno2,3-b pyrrolizine synthesis antitumor activity |
| ISSN号 | 1005-9040 |
| 其他题名 | Synthesis and Biological Evaluation of Novel Tricyclic Oximino Derivatives as Antitumor Agents |
| 英文摘要 | A series of novel alkylthio/sulfinyl-8H-thieno2,3-bpyrrolizin-8-oximino derivatives V-1-VIII15 were designed and synthesized as antitumor agents. Their structures were confirmed using IF, H-1 NMR, elemental analysis, and MS. The antitumor activities of all the target compounds were tested by the MTT method in vitro against Bel-7402, HT-1080, SGC-7901, and A549 Cell Lines. Among them, compound VI9 displayed a promising antitumor activity superior to that of Cisplatin. |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3251192 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/147879]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | Guo Shuchun,Zhao Yanfang,Li Rongdong,et al. Synthesis and biological evaluation of novel tricyclic oximino derivatives as antitumor agents[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2008,24(1):47-53. |
| APA | Guo Shuchun,Zhao Yanfang,Li Rongdong,Xie Lijun,Yang Youbin,&Gong Ping.(2008).Synthesis and biological evaluation of novel tricyclic oximino derivatives as antitumor agents.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,24(1),47-53. |
| MLA | Guo Shuchun,et al."Synthesis and biological evaluation of novel tricyclic oximino derivatives as antitumor agents".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 24.1(2008):47-53. |
入库方式： OAI收割
来源：金属研究所
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