Lymph Node Metastasis in Early Signet Ring Cell Carcinoma: Endoscopic Mucosal Resection
文献类型：期刊论文
| 作者 | Li Hua1; Lu Ping1; Zhang Jing2; Xu Huimian1; Wang Shubao1; Chen Junqing1 |
| 刊名 | CHINESE JOURNAL OF CANCER RESEARCH
 |
| 出版日期 | 2008 |
| 卷号 | 20期号:4页码:274-278 |
| 关键词 | EARLY GASTRIC-CANCER ELECTROSURGICAL KNIFE Early signet ring cell carcinoma LNM Clinicopathological characteristics Endoscopic mucosal resection |
| ISSN号 | 1000-9604 |
| 其他题名 | Lymph node metastasis in early signet ring cell carcinoma: Endoscopic mucosal resection |
| 英文摘要 | Objective: To identify clinicopathological factors predictive of lymph node metastases (LNM) in early signet ring cell carcinoma (SRC), and further to expand the possibility of using endoscopic mucosal resection (EMR) for the treatment of early SRC. Methods: Data from 27 surgically treated patients with early SRC were collected, and the association between the clinicopathological factors and the presence of LNM was retrospectively analyzed by univariate and multivariate logistic regression analyses. Results: In the univariate analysis, a tumor larger than 3.0 cm, submucosal invasion, and the presence of lymphatic vessel involvement (LVI) were significantly associated with a higher rate of LNM (all P<0.05). In the multivariate model, the presence of LVI was found of to be an independent pathological risk factor for LNM. There was no LNM in 14 patients without the three clinicopathological risk factors (a tumor larger than 3.0 cm, submucosal invasion, and the presence of LVI). Conclusion: EMR alone may be sufficient treatment for intramucosal early SRC if the tumor is less than or equal to 3.0 cm in size, and when LVI is absent upon postoperative histological examination. When specimens show LVI, an additional radical gastrectomy with lymphadenectomy should be recommended. |
| 资助项目 | [Nature Science Foundation of Liaoning Province] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3427189 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/149121]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.中国科学院金属研究所 2.华东师范大学 |
| 推荐引用方式 GB/T 7714 | Li Hua,Lu Ping,Zhang Jing,et al. Lymph Node Metastasis in Early Signet Ring Cell Carcinoma: Endoscopic Mucosal Resection[J]. CHINESE JOURNAL OF CANCER RESEARCH,2008,20(4):274-278. |
| APA | Li Hua,Lu Ping,Zhang Jing,Xu Huimian,Wang Shubao,&Chen Junqing.(2008).Lymph Node Metastasis in Early Signet Ring Cell Carcinoma: Endoscopic Mucosal Resection.CHINESE JOURNAL OF CANCER RESEARCH,20(4),274-278. |
| MLA | Li Hua,et al."Lymph Node Metastasis in Early Signet Ring Cell Carcinoma: Endoscopic Mucosal Resection".CHINESE JOURNAL OF CANCER RESEARCH 20.4(2008):274-278. |
入库方式： OAI收割
来源：金属研究所
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