A non-opioid pathway for dynorphin-caused spinal cord injury in rats
文献类型：期刊论文
| 作者 | Chen Yu; Xiang Liangbi; Liu Jun; Zhou Dapeng; Yu Hailong; Wang Qi; Han Wenfeng; Guo Mingming |
| 刊名 | NEURAL REGENERATION RESEARCH
 |
| 出版日期 | 2012 |
| 卷号 | 7期号:11页码:815-820 |
| 关键词 | PROSTATIC ACID-PHOSPHATASE RECEPTOR ANTAGONIST PAIN SENSITIZATION NEURONS MK-801 NMDA INHIBITION TRAUMA spinal cord injury dynorphin kappa opioid receptor antagonist N-methyl-D-aspartate receptor antagonist motor function acid phosphatase |
| ISSN号 | 1673-5374 |
| 其他题名 | A non-opioid pathway for dynorphin-caused spinal cord injury in rats ☆ |
| 英文摘要 | Intrathecal injection of dynorphin into rats via subarachnoid catheter induces damage to spinal cord tissue and motor function. Injection of the kappa opioid receptor antagonist nor-binaltorphine, or the excitatory amino acid N-methyl-D-aspartate receptor antagonist MK-801 into rats alleviated the pathological changes of dynorphin-caused spinal cord tissue injury and reduced the acid phosphatase activity in the spinal cord. The experimental findings indicate that there are opioid and non-opioid pathways for dynorphin-induced spinal cord injury, and that the non-opioid receptor pathway may be mediated by the excitatory amino acid N-methyl-D-aspartate receptor. |
| 资助项目 | [Science and Key Technology Research and Development Program of Liaoning Province] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:4530874 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/149388]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | Chen Yu,Xiang Liangbi,Liu Jun,et al. A non-opioid pathway for dynorphin-caused spinal cord injury in rats[J]. NEURAL REGENERATION RESEARCH,2012,7(11):815-820. |
| APA | Chen Yu.,Xiang Liangbi.,Liu Jun.,Zhou Dapeng.,Yu Hailong.,...&Guo Mingming.(2012).A non-opioid pathway for dynorphin-caused spinal cord injury in rats.NEURAL REGENERATION RESEARCH,7(11),815-820. |
| MLA | Chen Yu,et al."A non-opioid pathway for dynorphin-caused spinal cord injury in rats".NEURAL REGENERATION RESEARCH 7.11(2012):815-820. |
入库方式： OAI收割
来源：金属研究所
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