Simply air: Vanadium-catalyzed oxidative kinetic resolution of methyl o-chloromandelate by ambient air
文献类型：期刊论文
| 作者 | Yin Lu1; Jia Xian1; Li Xing Shu2; Chan Albert S C1 |
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2010 |
| 卷号 | 21期号:7页码:774-777 |
| 关键词 | RACEMIC SECONDARY ALCOHOLS RECOMBINANT ESCHERICHIA-COLI CHIRAL NHC-PD(II) COMPLEXES ALPHA-HYDROXY ESTERS AEROBIC OXIDATION MOLECULAR-OXYGEN SALEN COMPLEXES (R)-O-CHLOROMANDELATE (-)-SPARTEINE MODEL Ambient air Vanadium-catalyzed OKR Methyl o-chloromandelate Schiff base ligands |
| ISSN号 | 1001-8417 |
| 其他题名 | Simply air: Vanadium-catalyzed oxidative kinetic resolution of methyl o-chloromandelate by ambient air |
| 英文摘要 | Vanadium-catalyzed oxidative kinetic resolution (OKR) of methyl o-chloromandelate 2a, key intermediate of the well-known oral antiplatelet agent (S)-clopidogrel, was achieved by ambient air for the first time. The air oxidation system, which was composed of vanadium and tridentate Schiff base ligands derived from amino alcohols and salicylaldehyde derivatives, afforded an efficient and economic approach to the target intermediate with high enantioselectivities (>99% ee). (C) 2010 Xian Jia. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
| 资助项目 | [National Natural Science Foundation of China] ; [Ministry of Education] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3924935 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/151115]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.中国科学院金属研究所 2.中国科学院广州地球化学研究所 |
| 推荐引用方式 GB/T 7714 | Yin Lu,Jia Xian,Li Xing Shu,et al. Simply air: Vanadium-catalyzed oxidative kinetic resolution of methyl o-chloromandelate by ambient air[J]. CHINESE CHEMICAL LETTERS,2010,21(7):774-777. |
| APA | Yin Lu,Jia Xian,Li Xing Shu,&Chan Albert S C.(2010).Simply air: Vanadium-catalyzed oxidative kinetic resolution of methyl o-chloromandelate by ambient air.CHINESE CHEMICAL LETTERS,21(7),774-777. |
| MLA | Yin Lu,et al."Simply air: Vanadium-catalyzed oxidative kinetic resolution of methyl o-chloromandelate by ambient air".CHINESE CHEMICAL LETTERS 21.7(2010):774-777. |
入库方式： OAI收割
来源：金属研究所
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