Synthesis and biological evaluation of new pyrrolopyrazinone compounds as potential antitumor agents
文献类型：期刊论文
| 作者 | Meng Ying1; Wang Guan2; Li Yue1; Hou Kuan1; Yuan Yue1; Zhang LiJuan1; Song HongRui1; Shi Wei2 |
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2013 |
| 卷号 | 24期号:7页码:619-621 |
| 关键词 | Pyrrolopyrazinone Antitumor Synthesis |
| ISSN号 | 1001-8417 |
| 其他题名 | Synthesis and biological evaluation of new pyrrolopyrazinone compounds as potential antitumor agents |
| 英文摘要 | A series of pyrrolo1,2-apyrazinone compounds (5a-9f) were synthesized, and their cytotoxic activity against SKOV-3, A549, HeLa cells in vitro were evaluated by the MU method. Some of the compounds showed potential antitumor activity against three tumor cell lines. Among them, compounds 9c and 9d showed the most potent cytotoxic activity. The preliminary mechanism of action was discussed. (C) 2013 Hong-Rui Song and Wei Shi. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
| 语种 | 英语 |
| CSCD记录号 | CSCD:4904853 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/151510]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.中国科学院金属研究所 2.吉林大学 |
| 推荐引用方式 GB/T 7714 | Meng Ying,Wang Guan,Li Yue,et al. Synthesis and biological evaluation of new pyrrolopyrazinone compounds as potential antitumor agents[J]. CHINESE CHEMICAL LETTERS,2013,24(7):619-621. |
| APA | Meng Ying.,Wang Guan.,Li Yue.,Hou Kuan.,Yuan Yue.,...&Shi Wei.(2013).Synthesis and biological evaluation of new pyrrolopyrazinone compounds as potential antitumor agents.CHINESE CHEMICAL LETTERS,24(7),619-621. |
| MLA | Meng Ying,et al."Synthesis and biological evaluation of new pyrrolopyrazinone compounds as potential antitumor agents".CHINESE CHEMICAL LETTERS 24.7(2013):619-621. |
入库方式： OAI收割
来源：金属研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。