Design, synthesis and biological evaluation of 1,4-dihydrothieno3 ',2 ':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists
文献类型：期刊论文
| 作者 | Sun Rui2; Song Jing2; Liu Si Jie2; Zhao Hui2; Yan Chun Li2; Zhang Ai Jun2; Koirala Diwa1; Li Da Wei1; Hu Chun2 |
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2011 |
| 卷号 | 22期号:3页码:256-259 |
| 关键词 | BETA Estrogen receptor antagonists Synthesis Biological activity Thiophene Pyrazole Thiopyran Piperazine |
| ISSN号 | 1001-8417 |
| 其他题名 | Design, synthesis and biological evaluation of 1,4-dihydrothieno3′,2′:5,6thiopyrano4,3- cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists |
| 英文摘要 | The estrogen receptor is a target for therapeutic agents for hormone replacement in menopausal women, osteoporosis, reproductive cancers such as breast cancer, uterine cancer and prostate cancer. 1,4-Dihydrothieno3',2':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives were designed, synthesized and biological evaluated as potential estrogen receptor antagonists. (C) 2010 Chun Hu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
| 资助项目 | [National Natural Science Foundation of China (NSFC)] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:4149926 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/151616]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.上海交通大学 2.上海市地震局 3.中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | Sun Rui,Song Jing,Liu Si Jie,et al. Design, synthesis and biological evaluation of 1,4-dihydrothieno3 ',2 ':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists[J]. CHINESE CHEMICAL LETTERS,2011,22(3):256-259. |
| APA | Sun Rui.,Song Jing.,Liu Si Jie.,Zhao Hui.,Yan Chun Li.,...&Hu Chun.(2011).Design, synthesis and biological evaluation of 1,4-dihydrothieno3 ',2 ':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists.CHINESE CHEMICAL LETTERS,22(3),256-259. |
| MLA | Sun Rui,et al."Design, synthesis and biological evaluation of 1,4-dihydrothieno3 ',2 ':5,6thiopyrano4,3-cpyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists".CHINESE CHEMICAL LETTERS 22.3(2011):256-259. |
入库方式： OAI收割
来源：金属研究所
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