Design, synthesis, and fungicidal activity of novel 1,3,4-oxadiazole derivatives
文献类型：期刊论文
| 作者 | Yu Fuqiang1; Guan Aiying2; Li Mengru2; Hu Lan2; Li Xiaowu1 |
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2018 |
| 卷号 | 29期号:6页码:915-918 |
| 关键词 | INSECTICIDAL ACTIVITIES SAR 1,3,4-Oxadiazole derivatives Intermediate derivatization method Rice sheath blight Sorghum anthracnose Structure-activity relationship |
| ISSN号 | 1001-8417 |
| 英文摘要 | Employing the intermediate derivatization method (IDM), twenty novel 1,3,4-oxadiazole derivatives containing arylpyrazoloxyl moiety were designed and synthesized. The structures of the title compounds were identified by H-1 NMR,C-13 NMR, MS and elemental analyses, compound 4 was further identified by single-crystal X-ray diffraction. Antifungal activities against rice sheath blight (RSB) and sorghum anthracnose (SA) were evaluated by the mycelium linear growth rate method. Compounds 4,16 and 20 displayed significant activities against RSB (EC50 = 0.88 mg/L, 0.91 mg/L and 0.85 mg/L, respectively), higher than the reference tebuconazole; While compound 3 exhibited higher activity against SA (EC50 = 1.03 mg/L), equal to commercial pyraclostrobin (EC50= 1.06 mg/L). The study showed that compound 20 is a promising fungicide for further development. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved. |
| 资助项目 | [Open Foundation of Key Laboratory for Anisotropy and Texture of Materials, Ministry of Education, Northeastern University, China] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:6275686 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/152493]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.上海市地震局 2.中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | Yu Fuqiang,Guan Aiying,Li Mengru,et al. Design, synthesis, and fungicidal activity of novel 1,3,4-oxadiazole derivatives[J]. CHINESE CHEMICAL LETTERS,2018,29(6):915-918. |
| APA | Yu Fuqiang,Guan Aiying,Li Mengru,Hu Lan,&Li Xiaowu.(2018).Design, synthesis, and fungicidal activity of novel 1,3,4-oxadiazole derivatives.CHINESE CHEMICAL LETTERS,29(6),915-918. |
| MLA | Yu Fuqiang,et al."Design, synthesis, and fungicidal activity of novel 1,3,4-oxadiazole derivatives".CHINESE CHEMICAL LETTERS 29.6(2018):915-918. |
入库方式： OAI收割
来源：金属研究所
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