Why does a high-fat diet induce preeclampsia-like symptoms in pregnant rats?
文献类型：期刊论文
| 作者 | Ge Jing2; Wang Jun2; Xue Dan2; Zhu Zhengsheng1; Chen Zhenyu2; Li Xiaoqiu2; Su Dongfeng2; Du Juan2 |
| 刊名 | NEURAL REGENERATION RESEARCH
 |
| 出版日期 | 2013 |
| 卷号 | 8期号:20页码:1872-1880 |
| 关键词 | PHOSPHOLIPASE A(2) OXIDATIVE STRESS ISCHEMIC-STROKE ACIDS RISK COMPLICATIONS TRIGLYCERIDES METABOLISM DISEASE WOMEN neural regeneration preeclampsia eclampsia excitatory neurotransmitter neurotoxicity hyperlipidemia hypertension pregnancy lipoprotein-associated phospholipase A2 metabotropic glutamate receptor 1 grants-supported paper neuroregeneration |
| ISSN号 | 1673-5374 |
| 其他题名 | Why does a high-fat diet induce preeclampsia-like symptoms in pregnant rats |
| 英文摘要 | Changes in neurotransmitter levels in the brain play an important role in epilepsy-like attacks after pregnancy-induced preeclampsia-eclampsia. Metabotropic glutamate receptor 1 participates in the onset of lipid metabolism disorder-induced preeclampsia. Pregnant rats were fed with a high-fat diet for 20 days. Thus, these pregnant rats experienced preeclampsia-like syndromes such as hypertension and proteinuria. Simultaneously, metabotropic glutamate receptor 1 mRNA and protein expressions were upregulated in the rat hippocampus. These findings indicate that increased expression of metabotropic glutamate receptor 1 promotes the occurrence of high-fat diet-induced preeclampsia in pregnant rats. |
| 资助项目 | [Military Medical Science and Technology General Project] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:4902803 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/155010]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.Dantu Dist Sanit Supervis Institute, Zhenjiang 212001, Jiangsu, Peoples R China 2.中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | Ge Jing,Wang Jun,Xue Dan,et al. Why does a high-fat diet induce preeclampsia-like symptoms in pregnant rats?[J]. NEURAL REGENERATION RESEARCH,2013,8(20):1872-1880. |
| APA | Ge Jing.,Wang Jun.,Xue Dan.,Zhu Zhengsheng.,Chen Zhenyu.,...&Du Juan.(2013).Why does a high-fat diet induce preeclampsia-like symptoms in pregnant rats?.NEURAL REGENERATION RESEARCH,8(20),1872-1880. |
| MLA | Ge Jing,et al."Why does a high-fat diet induce preeclampsia-like symptoms in pregnant rats?".NEURAL REGENERATION RESEARCH 8.20(2013):1872-1880. |
入库方式： OAI收割
来源：金属研究所
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