Diagnosis of Tumor-Like Polypoid Lesions of Gallbladder by Serum Proteomic Fingerprint
文献类型：期刊论文
| 作者 | Ge Chunlin1; Luan Fengming1; Ma Ning1; Li Yongzhe2; Hu Chaojun2; Li Ning2 |
| 刊名 | CHINESE JOURNAL OF CANCER RESEARCH
 |
| 出版日期 | 2008 |
| 卷号 | 20期号:4页码:286-289 |
| 关键词 | FLIGHT MASS-SPECTROMETRY SELDI-TOF-MS CANCER IDENTIFICATION DISCOVERY BIOMARKERS CARCINOMA BREAST TIME Gallbladder disease Diagnosis Specific proteins Surface enhanced laser desorption/ionization time of flight mass spectrometry |
| ISSN号 | 1000-9604 |
| 其他题名 | Diagnosis of tumor-like polypoid lesions of gallbladder by serum proteomic fingerprint |
| 英文摘要 | Objective: To search the specific serum proteins in tumor-like polypoid lesions of the gallbladder(PLG) patients. Methods: Surface enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-MS) technique and WCX Magnetic Beads were used to detect the serum proteomic fingerprint of 23 patients with tumor-like PLG, 21 patients with non tumor-like PLG and 26 normal persons. Biomarker Wizard and Biomarker Patterns Software were used in combination to analyze the data. Results: In the preliminary screening, 22 representative specific proteins for tumor-like PLG were found. Seven specific proteins showed increased expression and 15 specific proteins showed decreased expression in the tumor-like PLG patients. Three specific proteins are selected for the diagnosis of the tumor-like PLG.. Conclusion: SELDI-TOF-MS technique can be used to select specific proteins for tumor-like PLG patients, which may be useful for the diagnosis of the tumor-like PLG and the differential diagnosis with the non tumor-like PLG. |
| 资助项目 | [Scientific Research Foundation of the High School from Education Department of Liaoning Province] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3427191 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/158088]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.中国科学院金属研究所 2.Beijing Union Med Coll Hosp, Peking Union Med Coll, Department Clin Lab, Beijing 100730, Peoples R China 3.中国医学科学院 |
| 推荐引用方式 GB/T 7714 | Ge Chunlin,Luan Fengming,Ma Ning,et al. Diagnosis of Tumor-Like Polypoid Lesions of Gallbladder by Serum Proteomic Fingerprint[J]. CHINESE JOURNAL OF CANCER RESEARCH,2008,20(4):286-289. |
| APA | Ge Chunlin,Luan Fengming,Ma Ning,Li Yongzhe,Hu Chaojun,&Li Ning.(2008).Diagnosis of Tumor-Like Polypoid Lesions of Gallbladder by Serum Proteomic Fingerprint.CHINESE JOURNAL OF CANCER RESEARCH,20(4),286-289. |
| MLA | Ge Chunlin,et al."Diagnosis of Tumor-Like Polypoid Lesions of Gallbladder by Serum Proteomic Fingerprint".CHINESE JOURNAL OF CANCER RESEARCH 20.4(2008):286-289. |
入库方式： OAI收割
来源：金属研究所
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