Discovery of multi-drug resistant, MCR-1 and ESBL-coproducing ST117 Escherichia coli from diseased chickens in northeast China
文献类型：期刊论文
| 作者 | Ding Sijia1; Han Xiaohu2; Li Jun3; Gao Weifan2; Chen Zeliang2; Feng Youjun3 |
| 刊名 | SCIENCE BULLETIN
 |
| 出版日期 | 2018 |
| 卷号 | 63期号:16页码:1059-1066 |
| 关键词 | RESOLUTION CRYSTAL-STRUCTURE VI SECRETION KLEBSIELLA-PNEUMONIAE CATALYTIC DOMAIN BETA-LACTAMASE ANTIBIOTIC-RESISTANCE SALMONELLA-ENTERICA GENE MCR-1 PLASMID INFECTIONS Lipid A MCR-1 Colistin resistance Transferable resistance to polymyxin Intrinsic colistin resistance Gut bacteria Microbiome |
| ISSN号 | 2095-9273 |
| 英文摘要 | An endemic multi-drug resistant ST117 E. coli isolate coproducing MCR-1 and 3 ESBL loci was, for the first time, detected from diseased chicken, Liaoning Province, in Northeast China, from 2011 to 2012. Whole-genome sequencing revealed 5 unique plasmids, namely pHXH-1, pHXH-2, pHXH-3, pHXH-4 and pHXH-5). Among them, pHXH1 and pHXH4 encode ESBL, and pHXH-5 mediates MCR-1 colistin resistance. The results indicate that the potentially-national dissemination of MCR-1-positive pathogens with pan-drug resistance proceeds via food chains. (C) 2018 Science China Press. Published by Elsevier B.V. and Science China Press. All rights reserved. |
| 资助项目 | [National Key R&D Program of China] ; [National Key Basic Research Program of China] ; [National Natural Science Foundation of China] ; ["Young 1000 Talents" Award] |
| 语种 | 英语 |
| CSCD记录号 | CSCD:6337004 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/158239]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | 1.Zhejiang Chinese Med University, Sch Stomatol, Hangzhou 310053, Zhejiang, Peoples R China Sch Stomatol 2.中国科学院金属研究所 3.浙江大学 |
| 推荐引用方式 GB/T 7714 | Ding Sijia,Han Xiaohu,Li Jun,et al. Discovery of multi-drug resistant, MCR-1 and ESBL-coproducing ST117 Escherichia coli from diseased chickens in northeast China[J]. SCIENCE BULLETIN,2018,63(16):1059-1066. |
| APA | Ding Sijia,Han Xiaohu,Li Jun,Gao Weifan,Chen Zeliang,&Feng Youjun.(2018).Discovery of multi-drug resistant, MCR-1 and ESBL-coproducing ST117 Escherichia coli from diseased chickens in northeast China.SCIENCE BULLETIN,63(16),1059-1066. |
| MLA | Ding Sijia,et al."Discovery of multi-drug resistant, MCR-1 and ESBL-coproducing ST117 Escherichia coli from diseased chickens in northeast China".SCIENCE BULLETIN 63.16(2018):1059-1066. |
入库方式： OAI收割
来源：金属研究所
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