A survey and systematic assessment of computational methods for drug response prediction
文献类型：期刊论文
| 作者 | Chen, Jinyu1,2; Zhang, Louxin3,4 |
| 刊名 | BRIEFINGS IN BIOINFORMATICS
 |
| 出版日期 | 2021 |
| 卷号 | 22期号:1页码:232-246 |
| 关键词 | Drug response prediction regression model low rank matrix factorization based approach Bayesian inference deep learning benchmark |
| ISSN号 | 1467-5463 |
| DOI | 10.1093/bib/bbz164 |
| 英文摘要 | Drug response prediction arises from both basic and clinical research of personalized therapy, as well as drug discovery for cancers. With gene expression profiles and other omics data being available for over 1000 cancer cell lines and tissues, different machine learning approaches have been applied to drug response prediction. These methods appear in a body of literature and have been evaluated on different datasets with only one or two accuracy metrics. We systematically assess 17 representative methods for drug response prediction, which have been developed in the past 5 years, on four large public datasets in nine metrics. This study provides insights and lessons for future research into drug response prediction. |
| 资助项目 | Singapore National Research Fund[NRF2016NRF-NSFC001-026] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Mathematical & Computational Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000634950200019 |
| 出版者 | OXFORD UNIV PRESS |
| 源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/58451]  |
| 专题 | 中国科学院数学与系统科学研究院 |
| 通讯作者 | Zhang, Louxin |
| 作者单位 | 1.Natl Univ Singapore, Dept Math, Singapore, Singapore 2.Chinese Acad Sci, Acad Math & Syst Sci, Beijing, Peoples R China 3.Natl Univ Singapore, Dept Math & Computat Biol Programme, Singapore 119076, Singapore 4.Univ Waterloo, Comp Sci, Waterloo, ON N2L 3G1, Canada |
| 推荐引用方式 GB/T 7714 | Chen, Jinyu,Zhang, Louxin. A survey and systematic assessment of computational methods for drug response prediction[J]. BRIEFINGS IN BIOINFORMATICS,2021,22(1):232-246. |
| APA | Chen, Jinyu,&Zhang, Louxin.(2021).A survey and systematic assessment of computational methods for drug response prediction.BRIEFINGS IN BIOINFORMATICS,22(1),232-246. |
| MLA | Chen, Jinyu,et al."A survey and systematic assessment of computational methods for drug response prediction".BRIEFINGS IN BIOINFORMATICS 22.1(2021):232-246. |
入库方式： OAI收割
来源：数学与系统科学研究院
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