Bio-inspired amyloid polypeptides: From self-assembly to nanostructure design and biotechnological applications
文献类型：期刊论文
| 作者 | Lai, Yi1; Li, Fenglin1; Zou, Zhifeng1; Saeed, Madiha2; Xu, Zhiai1; Yu, Haijun2
|
| 刊名 | APPLIED MATERIALS TODAY
 |
| 出版日期 | 2021-03-01 |
| 卷号 | 22页码:23 |
| 关键词 | Amyloid polypeptide Bio-inspired Nanomedicine Self-assembly |
| ISSN号 | 2352-9407 |
| DOI | 10.1016/j.apmt.2021.100966 |
| 通讯作者 | Xu, Zhiai(zaxu@chem.ecnu.edu.cn) ; Yu, Haijun(hjyu@simm.ac.cn) |
| 英文摘要 | The aggregation of amyloid polypeptide plays a crucial role in inducing various chronic diseases, such as neurodegenerative diseases and type II diabetes. Up to date, amyloid polypeptide-based nanostructures have been extensively investigated for various biotechnological applications while exploiting the pathogenic mechanism of amyloid polypeptide-related diseases. Despite extensive and significant progress having been made, the fundamental understanding and the strategies to organize amyloid polypeptide nanomaterials remain elusive. Herein, the blooming developments of bio-inspired self assembled amyloid polypeptide nanostructures on synthesis, properties and applications are mainly introduced. We begin with an emphasis of the importance of thermodynamic and kinetic factors on the self-assembly. Second, the cutting-edge advances and challenges for engineering of amyloid peptide based nanomaterials on multiple dimensions are summarized. Finally, the comprehensive applications in biosensing, bioimaging, drug/gene delivery, cellular scaffolds and air pollution governance of amyloid polypeptide-based nanomaterials are presented. Through summarizing these aspects of amyloid polypeptides, this review is expected to motivate researchers to devote more efforts to investigating of novel architectures and translating the artificial designs for intriguing applications. ? 2021 Elsevier Ltd. All rights reserved. |
| 资助项目 | National Natural Science Foundation of China[22074043] ; National Natural Science Foundation of China[21775046] ; Fundamental Research Funds for the Central Universities |
| WOS研究方向 | Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000632615400009 |
| 出版者 | ELSEVIER |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/295321]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Xu, Zhiai; Yu, Haijun |
| 作者单位 | 1.East China Normal Univ, Sch Chem & Mol Engn, Shanghai 200241, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med SIMM, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lai, Yi,Li, Fenglin,Zou, Zhifeng,et al. Bio-inspired amyloid polypeptides: From self-assembly to nanostructure design and biotechnological applications[J]. APPLIED MATERIALS TODAY,2021,22:23. |
| APA | Lai, Yi,Li, Fenglin,Zou, Zhifeng,Saeed, Madiha,Xu, Zhiai,&Yu, Haijun.(2021).Bio-inspired amyloid polypeptides: From self-assembly to nanostructure design and biotechnological applications.APPLIED MATERIALS TODAY,22,23. |
| MLA | Lai, Yi,et al."Bio-inspired amyloid polypeptides: From self-assembly to nanostructure design and biotechnological applications".APPLIED MATERIALS TODAY 22(2021):23. |
入库方式： OAI收割
来源：上海药物研究所
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