Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos
文献类型：期刊论文
| 作者 | Pan Hui-Qin1,2; Zhou Heng2; Miao Shui2; Guo De-An1 ; Zhang Xiao-Li3; Hu Qing2; Mao Xiu-Hong2; Ji Shen2
|
| 刊名 | CHINESE JOURNAL OF NATURAL MEDICINES
 |
| 出版日期 | 2021 |
| 卷号 | 19期号:1页码:70-80 |
| ISSN号 | 2095-6975 |
| 关键词 | Plant metabolomics Insecticide Metabolite variation Lonicerae Japonicae Flos |
| DOI | 10.1016/S1875-5364(21)60008-0 |
| 通讯作者 | Ji Shen(jishen2013@163.com) |
| 英文摘要 | Pesticides' overuse and misuse have been reported to induce ingredient variations in herbal medicine, which is now gaining attention in the medicinal field as a form of alternative medicine. To date, available studies on pesticide-induced ingredient variations of herbal medicine are limited only on a few compounds and remain most others unexamined. In this study, a plant metabolomics-based strategy was performed to systematically explore the effects of two frequently used insecticides on the comprehensive constituents of Lonicerae Japonicae Flos (LJF), the flower buds of Lonicera japonica Thunb.. Field trials were designed on a cultivating plot of L. japonica with controls and treatments of imidacloprid (IMI) and compound flonicamid and acetamiprid (CFA). Unbiased metabolite profiling was conducted by ultra-high performance liquid chromatography/quadrupole-Orbitrap mass spectrometer. After data pretreatment by automatic extraction and screening, a data matrix of metabolite features was submitted for statistical analyses. Consequently, 29 metabolic markers, including chlorogenic acids, iridoids and organic acid-glucosides were obtained and characterized. The relative quantitative assay was subsequently performed to monitor their variations across flowering developments. This is the first study that systematically explored the insecticide-induced metabolite variations of LJF while taking into account the inherent variability of flowering development. The results were beneficial for holistic quality assessment of LJF and significant for guiding scientific use of pesticides in the large-scale cultivation. |
| WOS关键词 | LIQUID-CHROMATOGRAPHY ; METABOLISM ; STEMS |
| 资助项目 | National Key R&D Program of China[2017YFC1700800] ; China Postdoctoral Science Foundation[2019M651551] ; Shanghai Science and Technology Commission[18DZ2292200] ; Shanghai Science and Technology Commission[18DZ2200900] |
| WOS研究方向 | Integrative & Complementary Medicine ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | CHINESE JOURNAL NATURAL MEDICINES |
| WOS记录号 | WOS:000613940000008 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/295648]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Ji Shen |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Natl Engn Lab TCM Standardizat Technol, Shanghai 201203, Peoples R China 2.Shanghai Inst Food & Drug Control, NMPA Key Lab Qual Control Tradit Chinese Med, Shanghai 201203, Peoples R China 3.Shanghai Kaibao Pharmaceut Co Ltd, Shanghai 201401, Peoples R China |
| 推荐引用方式 GB/T 7714 | Pan Hui-Qin,Zhou Heng,Miao Shui,et al. Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2021,19(1):70-80. |
| APA | Pan Hui-Qin.,Zhou Heng.,Miao Shui.,Guo De-An.,Zhang Xiao-Li.,...&Ji Shen.(2021).Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos.CHINESE JOURNAL OF NATURAL MEDICINES,19(1),70-80. |
| MLA | Pan Hui-Qin,et al."Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos".CHINESE JOURNAL OF NATURAL MEDICINES 19.1(2021):70-80. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。