Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures
文献类型：期刊论文
| 作者 | Jing, Shuxi2,3; Zeller, Wayne E.4; Ferreira, Daneel5,6; Zhou, Bin7; Nam, Joo-Won1; Bedran-Russo, Ana8; Chen, Shao-Nong2,3; Pauli, Guido F.2,3 |
| 刊名 | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
 |
| 出版日期 | 2020-11-25 |
| 卷号 | 68期号:47页码:13541-13549 |
| 关键词 | proanthocyanidins polyphenols nomenclature structure-activity relationships |
| ISSN号 | 0021-8561 |
| DOI | 10.1021/acs.jafc.0c05392 |
| 通讯作者 | Pauli, Guido F.(gfp@uic.edu) |
| 英文摘要 | Proanthocyanidins (PACs) are near-ubiquitous and chemically complex metabolites, prototypical of higher plants. Their roles in food/feed/nutrition and ethnomedicine are widely recognized but poorly understood. With the analysis of evidence that underlies this challenge, this perspective identifies shortcomings in capturing and delineating PAC structures as key factors. While several groups have forwarded new representations, a consensus method that captures PAC structures concisely and offers high integrity for electronic storage is required to reduce confusion in this expansive field. The PAC block arrays (PACBAR) system fills this gap by providing precise and human- and machine-readable structural descriptors that capture PAC metabolomic structural diversity. PACBAR enables communication of PAC structures for the development of precise structure-activity relationships and will assist in advancing PAC research to the next level. |
| 资助项目 | University of Illinois at Chicago ; Marquette University ; National Institute of Dental and Craniofacial Research (NIDCR)/National Institutes of Health (NIH)[R01 DE021040] ; National Institute of Dental and Craniofacial Research (NIDCR)/National Institutes of Health (NIH)[R56 DE021040] ; National Institute of Dental and Craniofacial Research (NIDCR)/National Institutes of Health (NIH)[R01 DE028194] |
| WOS研究方向 | Agriculture ; Chemistry ; Food Science & Technology |
| 语种 | 英语 |
| WOS记录号 | WOS:000595545400022 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/296164]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Pauli, Guido F. |
| 作者单位 | 1.Yeungnam Univ, Coll Pharm, Gyongsan 38541, Gyeongsangbuk D, South Korea 2.Univ Illinois, Coll Pharm, Pharmacognosy Inst, Chicago, IL 60612 USA 3.Univ Illinois, Coll Pharm, Dept Pharmaceut Sci, Chicago, IL 60612 USA 4.ARS, US Dairy Forage Res Ctr, USDA, Madison, WI USA 5.Univ Mississippi, Natl Ctr Nat Prod Res, University, MS 38677 USA 6.Univ Mississippi, Dept Biomol Sci, Div Pharmacognosy, Sch Pharm, University, MS 38677 USA 7.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 8.Marquette Univ, Sch Dent, Dept Gen Dent Sci, Milwaukee, WI 53233 USA |
| 推荐引用方式 GB/T 7714 | Jing, Shuxi,Zeller, Wayne E.,Ferreira, Daneel,et al. Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2020,68(47):13541-13549. |
| APA | Jing, Shuxi.,Zeller, Wayne E..,Ferreira, Daneel.,Zhou, Bin.,Nam, Joo-Won.,...&Pauli, Guido F..(2020).Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,68(47),13541-13549. |
| MLA | Jing, Shuxi,et al."Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 68.47(2020):13541-13549. |
入库方式： OAI收割
来源：上海药物研究所
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