Chemical constituents from the South China sea soft coral Sinularia humilis
文献类型：期刊论文
| 作者 | Li, Jie1,2; Huan, Xia-Juan1; Wu, Meng-Jun1; Chen, Zi-Hui1; Chen, Bao1; Miao, Ze-Hong1; Guo, Yue-Wei1 ; Li, Xu-Wen1
|
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2020-11-28 |
| 页码 | 7 |
| 关键词 | Soft coral Sinularia humilis diterpenoids capnosane |
| ISSN号 | 1478-6419 |
| DOI | 10.1080/14786419.2020.1855645 |
| 通讯作者 | Guo, Yue-Wei(ywguo@simm.ac.cn) ; Li, Xu-Wen(xwli@simm.ac.cn) |
| 英文摘要 | A new diterpenoid with an unusual capnosane skeleton, sinuhumilol A (1), alone with twelve known diverse compounds (2-13), were isolated from the South China Sea soft coral Sinularia humilis. Their structures and stereochemistry were elucidated by extensive spectroscopic analysis, quantum chemical calculations, and/or by the comparison of the spectroscopic data with those reported in the literature. In bioassay, compound 11 exhibited interesting specific cytotoxicity against the human colon adenocarcinoma cell line HT-29 with IC50 value of 12.5 mu M. |
| 资助项目 | National Natural Science Foundation of China[81991521] ; National Natural Science Foundation of China[21672230] ; National Key Research and Development Program of China[2018YFC0310903] ; Drug Innovation Major Project[2018ZX09711-001-001-009] ; SKLDR/SIMM Project[SIMM1903ZZ-04] ; Shanghai Rising-Star Program[20QA1411100] ; SA-SIBS Scholarship Program |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000601342400001 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/296319]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Guo, Yue-Wei; Li, Xu-Wen |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai, Peoples R China 2.Univ Sci & Technol China, Nano Sci & Technol Inst, Suzhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Jie,Huan, Xia-Juan,Wu, Meng-Jun,et al. Chemical constituents from the South China sea soft coral Sinularia humilis[J]. NATURAL PRODUCT RESEARCH,2020:7. |
| APA | Li, Jie.,Huan, Xia-Juan.,Wu, Meng-Jun.,Chen, Zi-Hui.,Chen, Bao.,...&Li, Xu-Wen.(2020).Chemical constituents from the South China sea soft coral Sinularia humilis.NATURAL PRODUCT RESEARCH,7. |
| MLA | Li, Jie,et al."Chemical constituents from the South China sea soft coral Sinularia humilis".NATURAL PRODUCT RESEARCH (2020):7. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。