Biomimetic camouflage delivery strategies for cancer therapy
文献类型：期刊论文
| 作者 | Asrorov, Akmal M.2,3; Gu, Zeyun2; Li, Feng4; Liu, Lingyun5; Huang, Yongzhuo1,2,6
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| 刊名 | NANOSCALE
 |
| 出版日期 | 2021-05-04 |
| 页码 | 14 |
| ISSN号 | 2040-3364 |
| DOI | 10.1039/d1nr01127h |
| 通讯作者 | Li, Feng(fzl0023@auburn.edu) ; Huang, Yongzhuo(yzhuang@simm.ac.cn) |
| 英文摘要 | Cancer remains a significant challenge despite the progress in developing different therapeutic approaches. Nanomedicine has been explored as a promising novel cancer therapy. Recently, biomimetic camouflage strategies have been investigated to change the bio-fate of therapeutics and target cancer cells while reducing the unwanted exposure on normal tissues. Endogenous components (e.g., proteins, polysaccharides, and cell membranes) have been used to develop anticancer drug delivery systems. These biomimetic systems can overcome biological barriers and enhance tumor cell-specific uptake. The tumor-targeting mechanisms include ligand-receptor interactions and stimuli-responsive (e.g., pH-sensitive and light-sensitive) delivery. Drug delivery carriers composed of endogenous components represent a promising approach for improving cancer treatment efficacy. In this paper, different biomimetic drug delivery strategies for cancer treatment are reviewed with a focus on the discussion of their advantages and potential applications. |
| WOS关键词 | LOW-DENSITY-LIPOPROTEIN ; MESOPOROUS SILICA NANOPARTICLES ; HYALURONIC-ACID ; DRUG-DELIVERY ; TARGETED DELIVERY ; ALBUMIN NANOPARTICLES ; PHOTODYNAMIC THERAPY ; ERYTHROCYTE-MEMBRANE ; CO-DELIVERY ; TUMOR |
| 资助项目 | National Key Research and Development Program of China[2019YFE0129400] ; NFSC[81925035] ; NFSC[81521005] ; National Special Project for Significant New Drugs Development[2018ZX09711002-010002] ; Shanghai Sci-Tech Innovation Action Plan[19431903100] ; CAS PIFI Fellowship[2019PB0076] ; Belt & Road Young Scientist Award (Shanghai)[18430740800] ; Guangzhou Science and Technology Planning Project[201707010319] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000646799100001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/296501]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Li, Feng; Huang, Yongzhuo |
| 作者单位 | 1.NMPA Key Lab Qual Res & Evaluat Pharmaceut Excipi, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd, Shanghai 201203, Peoples R China 3.Acad Sci Uzbek, Inst Bioorgan Chem, 83 M Ulughbek St, Tashkent 100125, Uzbekistan 4.Auburn Univ, Harrison Sch Pharm, Auburn, AL 36849 USA 5.Guangzhou Univ Chinese Med, Clin Sch 1, Guangzhou 510450, Peoples R China 6.Chinese Acad Sci, Zhongshan Inst Drug Discovery, Inst Drug Discovery & Dev, Zhongshan 528437, Peoples R China |
| 推荐引用方式 GB/T 7714 | Asrorov, Akmal M.,Gu, Zeyun,Li, Feng,et al. Biomimetic camouflage delivery strategies for cancer therapy[J]. NANOSCALE,2021:14. |
| APA | Asrorov, Akmal M.,Gu, Zeyun,Li, Feng,Liu, Lingyun,&Huang, Yongzhuo.(2021).Biomimetic camouflage delivery strategies for cancer therapy.NANOSCALE,14. |
| MLA | Asrorov, Akmal M.,et al."Biomimetic camouflage delivery strategies for cancer therapy".NANOSCALE (2021):14. |
入库方式： OAI收割
来源：上海药物研究所
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