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Stimuli-activatable nanomaterials for phototherapy of cancer

文献类型：期刊论文

作者Zhou, Mengjiao2; Liu, Xiao2,3,4; Chen, Fangmin3,4; Yang, Lili2; Yuan, Minjian2; Fu, Ding-Yi2; Wang, Weiqi2,3,4; Yu, Haijun1,3,4; Yu,Haijun
刊名BIOMEDICAL MATERIALS
出版日期2021-07-01
卷号16期号:4页码:11
ISSN号1748-6041
关键词cancer treatment photodynamic therapy photothermal therapy intelligent nanomaterials stimuli-responsiveness
DOI10.1088/1748-605X/abfa6e
通讯作者Wang, Weiqi(wwq1990@ntu.edu.cn) ; Yu, Haijun(hjyu@simm.ac.cn)
英文摘要Phototherapy including photothermal therapy (PTT) and photodynamic therapy (PDT), as non-invasive therapy approaches, have gained accumulated attention for cancer treatment in past years. PTT and PDT can generate local hyperthermia effects and reactive oxygen species (ROS) respectively, for tumor eradication. To improve the therapeutic performance while minimizing the reverse side effects of phototherapy, extensive efforts have been devoted to developing stimuli-activatable (e.g. pH, redox, ROS, enzyme, etc) nanomaterials for tumor-specific delivery/activation of the phototherapeutics. In this review, we first overviewed the recent advances of the engineered stimuli-responsive nanovectors for the phototherapy of cancer. We particularly summarized the progress of stimuli-activatable nanomaterials-based combinatory therapy strategies for augmenting the performance of phototherapy. We further discuss challenges for the clinical translation of nanomaterials-based phototherapy.
WOS关键词METAL-ORGANIC FRAMEWORKS ; PHOTODYNAMIC THERAPY ; INORGANIC NANOMATERIALS ; NANOPARTICLES ; TUMORS ; ROS
资助项目National Natural Science Foundation of China[31900990] ; Youth Natural Science Fund of Jiangsu Province[BK20200977] ; Youth Natural Science Fund of Jiangsu Province[BK20200972] ; Nantong Municipal Science and Technology Project[JC2019103] ; Jiangsu College Students'Innovation and Entrepreneurship Training Program[202010304124Y] ; Jiangsu College Students'Innovation and Entrepreneurship Training Program[201910304124Y] ; Basic Research Program of Shenzhen, Science and Technology Development Fund[JCYJ20180227175420974]
WOS研究方向Engineering ; Materials Science
语种英语
出版者IOP PUBLISHING LTD
WOS记录号WOS:000649642000001
源URL[http://119.78.100.183/handle/2S10ELR8/296670]  
专题新药研究国家重点实验室
通讯作者Wang, Weiqi; Yu, Haijun; Yu,Haijun
作者单位1.Peking Univ, Shenzhen Inst, Shenzhen 518055, Peoples R China
2.Nantong Univ, Sch Pharm, Dept Pharmacol, Nantong 226000, Jiangsu, Peoples R China
3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
4.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Zhou, Mengjiao,Liu, Xiao,Chen, Fangmin,et al. Stimuli-activatable nanomaterials for phototherapy of cancer[J]. BIOMEDICAL MATERIALS,2021,16(4):11.
APA Zhou, Mengjiao.,Liu, Xiao.,Chen, Fangmin.,Yang, Lili.,Yuan, Minjian.,...&Yu,Haijun.(2021).Stimuli-activatable nanomaterials for phototherapy of cancer.BIOMEDICAL MATERIALS,16(4),11.
MLA Zhou, Mengjiao,et al."Stimuli-activatable nanomaterials for phototherapy of cancer".BIOMEDICAL MATERIALS 16.4(2021):11.

入库方式： OAI收割

来源：上海药物研究所

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