Thermolysin-triggered short peptides self-assembly in confined space and application in cell culturing
文献类型：期刊论文
| 作者 | Wang, Meiyue1,2; Wang, Anhe1,2; Li, Jieling1,2; Li, Qi1,2; Bai, Shuo1,2 |
| 刊名 | COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
 |
| 出版日期 | 2020-10-20 |
| 卷号 | 603页码:8 |
| ISSN号 | 0927-7757 |
| 关键词 | Self-assembly Short peptide Thermolysin Confined space AAO templates |
| DOI | 10.1016/j.colsurfa.2020.125213 |
| 英文摘要 | Molecules self-assembly in confined space such as in cell to form microfilaments is a crucial process to achieve special functionality. Herein, short peptides with different sequences were taken as examples to explore their self-assembly behavior in AAO templates which offer different pore size and depth to mimic confined environment. Thermolysin, as a mild, selective and effective biological enzyme, is applied here to trigger the self-assembly of short peptides in the pores of AAO template. Experimental results indicate that the morphology, structure and orientation of short peptide fibers in the pores are significantly affected by pore size of AAO templates. Moreover, the formed short peptide fibers in pores show obvious influence on the cell morphology and spreading. The method proposed here gives a feasible avenue to reveal the effect of confined environment on self-assembly behavior of short peptide. |
| WOS关键词 | BETA-SHEET ; DISCOVERY |
| 资助项目 | National Natural Science Foundation of China[21774132,21703253] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ELSEVIER |
| WOS记录号 | WOS:000571001200003 |
| 资助机构 | National Natural Science Foundation of China |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/42165]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Wang, Anhe; Bai, Shuo |
| 作者单位 | 1.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Meiyue,Wang, Anhe,Li, Jieling,et al. Thermolysin-triggered short peptides self-assembly in confined space and application in cell culturing[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2020,603:8. |
| APA | Wang, Meiyue,Wang, Anhe,Li, Jieling,Li, Qi,&Bai, Shuo.(2020).Thermolysin-triggered short peptides self-assembly in confined space and application in cell culturing.COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,603,8. |
| MLA | Wang, Meiyue,et al."Thermolysin-triggered short peptides self-assembly in confined space and application in cell culturing".COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 603(2020):8. |
入库方式： OAI收割
来源：过程工程研究所
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