中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 过程工程研究所
  3. 中国科学院过程工程研究所
Highly Efficient Conversion of Ketazines to Pyrazoline Derivatives Catalyzed by FeCl3

文献类型：期刊论文

作者Xia, Yangfeng3,4; Zhang, Xing1; Liu, Long3; Sun, Haiyun1; Zhao, Guoying3; Zhang, Yanqiang2,5
刊名INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
出版日期2020-10-21
卷号59期号:42页码:18748-18755
ISSN号0888-5885
DOI10.1021/acs.iecr.0c04032
英文摘要Pyrazoline derivatives as valuable five-membered heterocyclic compounds could be readily prepared through the intramolecular cyclization of ketazines. In this paper, transition metals (Zn2+, Cu2+, Cr3+, Mn2+, Co2+, Ni2+, and Fe3+) were applied for the catalytic synthesis of 3,5,5-trimethyl-2-pyrazoline, and FeCl3 showed the best catalytic performance with 95% conversion and 99% selectivity. Substrate screening exhibited that the steric hindrance of ketazines is a key factor on the conversions of R-substituted pyrazolines, following the order of R as methyl (95%) > ethyl (83%) > propyl (68%) > butyl (55%). Moreover, the mechanism of the cyclization of ketazines catalyzed by FeCl3 is calculated by density functional theory. The energetic profile shows that the cyclization reaction consists of two steps and FeCl3 can efficiently reduce their barrier energies. This work provides a feasible method for the preparation of pyrazoline derivatives using inexpensive, less toxic, and environmentally friendly FeCl3 as a catalyst.
WOS关键词TRANSITION-METAL SALTS ; ALPHA,BETA-UNSATURATED KETONES ; POLYMERIZATION ; DENSITY
资助项目National Natural Science Foundation of China[21878278] ; National Natural Science Foundation of China[21676281]
WOS研究方向Engineering
语种英语
WOS记录号WOS:000584932100003
出版者AMER CHEMICAL SOC
资助机构National Natural Science Foundation of China
源URL[http://ir.ipe.ac.cn/handle/122111/42725]  
专题中国科学院过程工程研究所
通讯作者Sun, Haiyun; Zhang, Yanqiang
作者单位1.Beijing Inst Aerosp Testing Technol, Beijing Key Lab Res & Applicat Aerosp Green Prope, Beijing 10074, Peoples R China
2.Zhengzhou Inst Emerging Ind Technol, Zhengzhou 450000, Peoples R China
3.Chinese Acad Sci, Beijing Key Lab Ion Liquids Clean Proc, Inst Proc Engn, Beijing 100049, Peoples R China
4.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China
5.Chinese Acad Sci, Key Lab Sci & Technol Particle Mat, Inst Proc Engn, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Xia, Yangfeng,Zhang, Xing,Liu, Long,et al. Highly Efficient Conversion of Ketazines to Pyrazoline Derivatives Catalyzed by FeCl3[J]. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,2020,59(42):18748-18755.
APA Xia, Yangfeng,Zhang, Xing,Liu, Long,Sun, Haiyun,Zhao, Guoying,&Zhang, Yanqiang.(2020).Highly Efficient Conversion of Ketazines to Pyrazoline Derivatives Catalyzed by FeCl3.INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,59(42),18748-18755.
MLA Xia, Yangfeng,et al."Highly Efficient Conversion of Ketazines to Pyrazoline Derivatives Catalyzed by FeCl3".INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH 59.42(2020):18748-18755.

入库方式： OAI收割

来源：过程工程研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。