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Advances of Nanoparticles for Leukemia Treatment

文献类型：期刊论文

作者Shen, Jie2,3; Lu, Zhiguo2,3; Wang, Jianze2; Zhang, Tianlu2; Yang, Jun2; Li, Yan2; Liu, Guiying1; Zhang, Xin2
刊名ACS BIOMATERIALS SCIENCE & ENGINEERING
出版日期2020-12-01
卷号6期号:12页码:6478-6489
关键词Leukemia Nanoparticles Delivery Drugs Microenvironment
ISSN号2373-9878
DOI10.1021/acsbiomaterials.0c01040
英文摘要Leukemia is a liquid tumor caused by a hematopoietic stem cell malignant clone, which seriously affects the normal function of the hematopoietic system. Conventional drugs have poor therapeutic effects due to their poor specificity and stability. With the development of nanotechnology, nonviral nanoparticles bring hope for the efficient treatment of leukemia. Nanoparticles are easily modified. They can be designed to target lesion sites and control drug release. Thereby, nanoparticles can improve the effects of drugs and reduce side effects. This review mainly focuses on and summarizes the current research progress of nanoparticles to deliver different leukemia therapeutic drugs, as to demonstrate the potential of nanoparticles in leukemia treatment.
WOS关键词ACUTE MYELOID-LEUKEMIA ; BONE-MARROW MICROENVIRONMENT ; HEMATOPOIETIC STEM-CELLS ; IN-VIVO ; DRUG-DELIVERY ; GEMTUZUMAB OZOGAMICIN ; PHOTODYNAMIC THERAPY ; CRISPR-CAS9 SYSTEM ; GOLD NANOPARTICLES ; ALZHEIMERS-DISEASE
资助项目National High Technology Research and Development Program[2016YFA0200303] ; Beijing Natural Science Foundation[L172046,2192057] ; National Natural Science Foundation of China[31771095] ; National Natural Science Foundation of China[21875254] ; National Natural Science Foundation of China[51573188]
WOS研究方向Materials Science
语种英语
WOS记录号WOS:000599989300002
出版者AMER CHEMICAL SOC
资助机构National High Technology Research and Development Program ; Beijing Natural Science Foundation ; National Natural Science Foundation of China
源URL[http://ir.ipe.ac.cn/handle/122111/42959]  
专题中国科学院过程工程研究所
通讯作者Liu, Guiying; Zhang, Xin
作者单位1.Capital Med Univ, Dept Pediat, Affiliated Beijing Anzhen Hosp, Beijing 100029, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Shen, Jie,Lu, Zhiguo,Wang, Jianze,et al. Advances of Nanoparticles for Leukemia Treatment[J]. ACS BIOMATERIALS SCIENCE & ENGINEERING,2020,6(12):6478-6489.
APA Shen, Jie.,Lu, Zhiguo.,Wang, Jianze.,Zhang, Tianlu.,Yang, Jun.,...&Zhang, Xin.(2020).Advances of Nanoparticles for Leukemia Treatment.ACS BIOMATERIALS SCIENCE & ENGINEERING,6(12),6478-6489.
MLA Shen, Jie,et al."Advances of Nanoparticles for Leukemia Treatment".ACS BIOMATERIALS SCIENCE & ENGINEERING 6.12(2020):6478-6489.

入库方式： OAI收割

来源：过程工程研究所

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