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Principles of regulating particle multiscale structures for controlling particle-cell interaction process

文献类型：期刊论文

作者Song, Cui1,2; Zhang, Xiao1; Wei, Wei1,2; Ma, Guanghui1,2
刊名CHEMICAL ENGINEERING SCIENCE
出版日期2021-03-15
卷号232页码:19
关键词Particles Multiscale structures Particle-cell interactions Biomedical applications
ISSN号0009-2509
DOI10.1016/j.ces.2020.116343
英文摘要Particles make extensively physical contact with cells after entering the body, which mediate a series of particle-cell interaction processes. These interaction processes induce different physiological responses of cells and indicate the potential biomedical applications of particles. Hence, controlling the particlecell interaction processes have been attracting more and more attentions. Among factors that affect particle-cell interaction processes, regulating particle multiscale structures is the most dominant. To date, numerous principles have been developed, including integrating particles with different physicochemical properties such as size, shape, elasticity and surface chemistry by various preparation technologies, coating particle surface with cell membrane to endow its biomimetic properties, taking advantage of the particle's dimensional effect, etc. In this review, we will highlight recent progresses on these princi ples, and corresponding biomedical applications in drug delivery, immune modulation and tissue engineering. The challenges and perspectives of regulating particle multiscale structures for controlling interaction processes will also be discussed. (C) 2020 Elsevier Ltd. All rights reserved.
WOS关键词RECEPTOR-MEDIATED ENDOCYTOSIS ; DRUG-DELIVERY SYSTEMS ; COATED GOLD NANOPARTICLES ; MESOPOROUS SILICA ; IMMUNE-RESPONSE ; GRAPHENE OXIDE ; IN-VITRO ; INTRACELLULAR TRAFFICKING ; TUMOR MICROENVIRONMENT ; MEMBRANE PENETRATION
资助项目Innovative Research Group Project of the National Natural Science Foundation of China[21821005] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB29040303]
WOS研究方向Engineering
语种英语
WOS记录号WOS:000608126300009
出版者PERGAMON-ELSEVIER SCIENCE LTD
资助机构Innovative Research Group Project of the National Natural Science Foundation of China ; Strategic Priority Research Program of the Chinese Academy of Sciences
源URL[http://ir.ipe.ac.cn/handle/122111/43224]  
专题中国科学院过程工程研究所
通讯作者Wei, Wei; Ma, Guanghui
作者单位1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Song, Cui,Zhang, Xiao,Wei, Wei,et al. Principles of regulating particle multiscale structures for controlling particle-cell interaction process[J]. CHEMICAL ENGINEERING SCIENCE,2021,232:19.
APA Song, Cui,Zhang, Xiao,Wei, Wei,&Ma, Guanghui.(2021).Principles of regulating particle multiscale structures for controlling particle-cell interaction process.CHEMICAL ENGINEERING SCIENCE,232,19.
MLA Song, Cui,et al."Principles of regulating particle multiscale structures for controlling particle-cell interaction process".CHEMICAL ENGINEERING SCIENCE 232(2021):19.

入库方式： OAI收割

来源：过程工程研究所

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