Natural orifice specimen extraction surgery versus conventional laparoscopic-assisted resection for colorectal cancer in elderly patients: a propensity-score matching study
文献类型：期刊论文
| 作者 | Zhang, Hao1; Hu, Hanqing1; Huang, Rui1; Guan, Zilong1; Zheng, Mingyu1; Xu, Chao1; Li, Zhengliang1; Wang, Yuliuming1; Zhang, Weiyuan1; Yu, Lei1 |
| 刊名 | UPDATES IN SURGERY
 |
| 出版日期 | 2021-08-09 |
| 关键词 | Natural orifice specimen extraction surgery Colorectal cancer Elderly patients Survival |
| ISSN号 | 2038-131X |
| DOI | 10.1007/s13304-021-01143-y |
| 通讯作者 | Wang, Guiyu(guiywang@163.com) ; Wang, Xishan(wxshan_1208@126.com) |
| 英文摘要 | Whether natural orifice specimen extraction surgery (NOSES) could provide beneficial effects in treating elderly patients is still under debate. The aim of the study was to compare the clinical outcomes of transanal NOSES with conventional laparoscopic-assisted resection (LA) in elderly colorectal cancer (CRC) patients. A retrospective analysis from the Second Affiliated Hospital of Harbin Medical University between 2013 and 2017 was performed. Outcomes related to surgery, body image, quality of life, anal function and long-term survival were compared between the two groups with the propensity-score matching (PSM) method. After PSM, 78 patients were successfully compared. Patients with NOSES had faster gastrointestinal function recovery (P = 0.028), less postoperative complications (P = 0.025), lower pain scores on days 1, 3 and 5 after surgery (P < 0.001). The body image score (P < 0.001) and cosmetic score (P < 0.001) were significantly higher in the NOSES group than the LA group at 1 month after surgery. Patients with NOSES posed better global health status (P < 0.001), role function (P = 0.009), emotional function (P = 0.011) and social function (P = 0.011) at 3 months after surgery. Moreover, NOSES showed non inferiority in anal function 6 months after surgery. No significant difference could be found regarding to overall survival (OS), disease-free survival (DFS), local recurrence (LR) and distant metastasis (DM). In elderly CRC patients, NOSES harbored favorable postoperative outcomes, excellent cosmetic properties and better quality of life. Besides, anal function and long-term outcomes of NOSES can be sure for elderly patients. |
| WOS关键词 | SURVIVAL OUTCOMES ; COLECTOMY ; TRIAL |
| 资助项目 | National Provincial Natural Fund[H2017016] ; National Natural Science Foundation of China[81872034] ; Wu Jieping Medical Foundation[320.6750.19092-41] |
| WOS研究方向 | Surgery |
| 语种 | 英语 |
| WOS记录号 | WOS:000683254500001 |
| 出版者 | SPRINGER-VERLAG ITALIA SRL |
| 资助机构 | National Provincial Natural Fund ; National Natural Science Foundation of China ; Wu Jieping Medical Foundation |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/123087]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Wang, Guiyu; Wang, Xishan |
| 作者单位 | 1.Harbin Med Univ, Dept Colorectal Surg, Affiliated Hosp 2, Harbin, Peoples R China 2.Univ Chinese Acad Sci, Zhejiang Canc Hosp, Dept Colorectal Surg, Canc Hosp, Hangzhou, Peoples R China 3.Chinese Acad Med Sci & Peking Union Med Coll, Natl Clin Res Ctr Canc, Dept Colorectal Surg, Natl Canc Ctr,Canc Hosp, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hao,Hu, Hanqing,Huang, Rui,et al. Natural orifice specimen extraction surgery versus conventional laparoscopic-assisted resection for colorectal cancer in elderly patients: a propensity-score matching study[J]. UPDATES IN SURGERY,2021. |
| APA | Zhang, Hao.,Hu, Hanqing.,Huang, Rui.,Guan, Zilong.,Zheng, Mingyu.,...&Wang, Xishan.(2021).Natural orifice specimen extraction surgery versus conventional laparoscopic-assisted resection for colorectal cancer in elderly patients: a propensity-score matching study.UPDATES IN SURGERY. |
| MLA | Zhang, Hao,et al."Natural orifice specimen extraction surgery versus conventional laparoscopic-assisted resection for colorectal cancer in elderly patients: a propensity-score matching study".UPDATES IN SURGERY (2021). |
入库方式： OAI收割
来源：合肥物质科学研究院
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